Ceftolozane–Tazobactam Pharmacokinetics in the Abdominal Tissue of Patients Undergoing Lower Gastrointestinal Surgery: Dosing Considerations Based on Site-Specific Pharmacodynamic Target Attainment

INTRODUCTION: Recently, complicated intra-abdominal infections (cIAI) have been caused not only by Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, and Pseudomonas aeruginosa, but also by extended-spectrum β-lactamase-producing Enterobacterales members. Ceftolozane–tazobactam (CTLZ–TAZ...

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Detalles Bibliográficos
Autores principales: Yoshimura, Kosuke, Ohge, Hiroki, Ikawa, Kazuro, Uegami, Shinnosuke, Watadani, Yusuke, Shigemoto, Norifumi, Hirano, Toshinori, Kitagawa, Hiroki, Kaiki, Yuki, Morikawa, Norifumi, Takahashi, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868209/
https://www.ncbi.nlm.nih.gov/pubmed/36418742
http://dx.doi.org/10.1007/s40121-022-00720-x

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