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Cardiac arrest associated with non-toxigenic corynebacterium diphtheria strain: A case report

Here we document a rare, acute, infection caused by non-toxigenic Corynebacterium diphtheriae and the resulting unique and severe clinical sequelae. Our patient was a young man with no known pre-existing conditions that presented in cardiopulmonary arrest. We contrast this case with prior instances...

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Autores principales: Alvarez, George V., Rupert, Deborah D., Sinclair, Samantha, Miyara, Santiago J., Guevara, Sara, Shih, Peter, Hoey, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868274/
https://www.ncbi.nlm.nih.gov/pubmed/36698824
http://dx.doi.org/10.3389/fmed.2022.1003193
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author Alvarez, George V.
Rupert, Deborah D.
Sinclair, Samantha
Miyara, Santiago J.
Guevara, Sara
Shih, Peter
Hoey, Cynthia
author_facet Alvarez, George V.
Rupert, Deborah D.
Sinclair, Samantha
Miyara, Santiago J.
Guevara, Sara
Shih, Peter
Hoey, Cynthia
author_sort Alvarez, George V.
collection PubMed
description Here we document a rare, acute, infection caused by non-toxigenic Corynebacterium diphtheriae and the resulting unique and severe clinical sequelae. Our patient was a young man with no known pre-existing conditions that presented in cardiopulmonary arrest. We contrast this case with prior instances of non-toxigenic C. diphtheriae strain infection in the United States and summarize the literature that suggests systemic infection can result in cardiogenic toxicity. We speculate on a possible missed, pre-existing condition that could have increased this patient’s susceptibility to poor clinical outcome.
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spelling pubmed-98682742023-01-24 Cardiac arrest associated with non-toxigenic corynebacterium diphtheria strain: A case report Alvarez, George V. Rupert, Deborah D. Sinclair, Samantha Miyara, Santiago J. Guevara, Sara Shih, Peter Hoey, Cynthia Front Med (Lausanne) Medicine Here we document a rare, acute, infection caused by non-toxigenic Corynebacterium diphtheriae and the resulting unique and severe clinical sequelae. Our patient was a young man with no known pre-existing conditions that presented in cardiopulmonary arrest. We contrast this case with prior instances of non-toxigenic C. diphtheriae strain infection in the United States and summarize the literature that suggests systemic infection can result in cardiogenic toxicity. We speculate on a possible missed, pre-existing condition that could have increased this patient’s susceptibility to poor clinical outcome. Frontiers Media S.A. 2023-01-09 /pmc/articles/PMC9868274/ /pubmed/36698824 http://dx.doi.org/10.3389/fmed.2022.1003193 Text en Copyright © 2023 Alvarez, Rupert, Sinclair, Miyara, Guevara, Shih and Hoey. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Alvarez, George V.
Rupert, Deborah D.
Sinclair, Samantha
Miyara, Santiago J.
Guevara, Sara
Shih, Peter
Hoey, Cynthia
Cardiac arrest associated with non-toxigenic corynebacterium diphtheria strain: A case report
title Cardiac arrest associated with non-toxigenic corynebacterium diphtheria strain: A case report
title_full Cardiac arrest associated with non-toxigenic corynebacterium diphtheria strain: A case report
title_fullStr Cardiac arrest associated with non-toxigenic corynebacterium diphtheria strain: A case report
title_full_unstemmed Cardiac arrest associated with non-toxigenic corynebacterium diphtheria strain: A case report
title_short Cardiac arrest associated with non-toxigenic corynebacterium diphtheria strain: A case report
title_sort cardiac arrest associated with non-toxigenic corynebacterium diphtheria strain: a case report
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868274/
https://www.ncbi.nlm.nih.gov/pubmed/36698824
http://dx.doi.org/10.3389/fmed.2022.1003193
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