Preclinical safety assessment of the suction-assisted intradermal injection of the SARS-CoV-2 DNA vaccine candidate pGO-1002 in white rabbit

pGO-1002, a non-viral DNA vaccine that expresses both spike and ORF3a antigens of SARS-CoV-2, is undergoing phase 1 and phase 2a clinical trials in Korea and the US. A preclinical repeated-dose toxicity study in New Zealand white rabbits in compliance with Good Laboratory Practice (GLP) was conducte...

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Detalles Bibliográficos
Autores principales: Oh, Seunghee, Jang, Min Seong, Jung, Kyung Jin, Han, Ji-Seok, Lee, Hyojin, Gil, Areum, Jeon, Bohyun, Roberts, Christine C., Maslow, Joel N., Kim, Yong-Bum, Han, Kang-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Biologics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868498/
https://www.ncbi.nlm.nih.gov/pubmed/36683063
http://dx.doi.org/10.1007/s00204-023-03446-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868498/
https://www.ncbi.nlm.nih.gov/pubmed/36683063
http://dx.doi.org/10.1007/s00204-023-03446-y

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