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A data-driven optimization method for coarse-graining gene regulatory networks

One major challenge in systems biology is to understand how various genes in a gene regulatory network (GRN) collectively perform their functions and control network dynamics. This task becomes extremely hard to tackle in the case of large networks with hundreds of genes and edges, many of which hav...

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Detalles Bibliográficos
Autores principales: Caranica, Cristian, Lu, Mingyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868542/
https://www.ncbi.nlm.nih.gov/pubmed/36698721
http://dx.doi.org/10.1016/j.isci.2023.105927