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A data-driven optimization method for coarse-graining gene regulatory networks
One major challenge in systems biology is to understand how various genes in a gene regulatory network (GRN) collectively perform their functions and control network dynamics. This task becomes extremely hard to tackle in the case of large networks with hundreds of genes and edges, many of which hav...
Autores principales: | Caranica, Cristian, Lu, Mingyang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868542/ https://www.ncbi.nlm.nih.gov/pubmed/36698721 http://dx.doi.org/10.1016/j.isci.2023.105927 |
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