Expression of KID syndromic mutation Cx26S17F produces hyperactive hemichannels in supporting cells of the organ of Corti

Some mutations in gap junction protein Connexin 26 (Cx26) lead to syndromic deafness, where hearing impairment is associated with skin disease, like in Keratitis Ichthyosis Deafness (KID) syndrome. This condition has been linked to hyperactivity of connexin hemichannels but this has never been demon...

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Detalles Bibliográficos
Autores principales: Abbott, Ana C., García, Isaac E., Villanelo, Felipe, Flores-Muñoz, Carolina, Ceriani, Ricardo, Maripillán, Jaime, Novoa-Molina, Joel, Figueroa-Cares, Cindel, Pérez-Acle, Tomas, Sáez, Juan C., Sánchez, Helmuth A., Martínez, Agustín D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868548/
https://www.ncbi.nlm.nih.gov/pubmed/36699003
http://dx.doi.org/10.3389/fcell.2022.1071202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868548/
https://www.ncbi.nlm.nih.gov/pubmed/36699003
http://dx.doi.org/10.3389/fcell.2022.1071202

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