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Diosgenin enhances liposome-enabled nucleic acid delivery and CRISPR/Cas9-mediated gene editing by modulating endocytic pathways

The CRISPR/Cas9 system holds great promise in treating genetic diseases, owing to its safe and precise genome editing. However, the major challenges to implementing the technology in clinics lie in transiently limiting the expression of genome editing factors and achieving therapeutically relevant f...

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Detalles Bibliográficos
Autores principales:	Lohchania, Brijesh, Christopher, Abisha Crystal, Arjunan, Porkizhi, Mahalingam, Gokulnath, Kathirvelu, Durga, Prasannan, Aishwarya, Venkatesan, Vigneshwaran, Taneja, Pankaj, KM, Mohan Kumar, Thangavel, Saravanabhavan, Marepally, Srujan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868636/ https://www.ncbi.nlm.nih.gov/pubmed/36698628 http://dx.doi.org/10.3389/fbioe.2022.1031049

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