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Comparison of prognosis of patients with endometrial cancer after hysteroscopy versus dilatation and curettage: A multicenter retrospective study

INTRODUCTION: Hysteroscopy is a useful procedure for diagnosing endometrial cancer. There is controversy regarding whether hysteroscopy affects the prognosis of endometrial cancer by prompting cancer cell into intraperitoneal dissemination. Our purpose was to confirm whether hysteroscopy could be a...

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Autores principales: Liu, Shihuang, Zhen, Lan, Zhang, Shaoyu, Cai, Yurong, Lin, Yanying, Chen, Fulian, Li, Xiaowen, You, Qianru, Lai, Xiaohong, Lai, Hangbo, Zheng, Xiangqin, Yi, Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868660/
https://www.ncbi.nlm.nih.gov/pubmed/36698830
http://dx.doi.org/10.3389/fmed.2022.1097133
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author Liu, Shihuang
Zhen, Lan
Zhang, Shaoyu
Cai, Yurong
Lin, Yanying
Chen, Fulian
Li, Xiaowen
You, Qianru
Lai, Xiaohong
Lai, Hangbo
Zheng, Xiangqin
Yi, Huan
author_facet Liu, Shihuang
Zhen, Lan
Zhang, Shaoyu
Cai, Yurong
Lin, Yanying
Chen, Fulian
Li, Xiaowen
You, Qianru
Lai, Xiaohong
Lai, Hangbo
Zheng, Xiangqin
Yi, Huan
author_sort Liu, Shihuang
collection PubMed
description INTRODUCTION: Hysteroscopy is a useful procedure for diagnosing endometrial cancer. There is controversy regarding whether hysteroscopy affects the prognosis of endometrial cancer by prompting cancer cell into intraperitoneal dissemination. Our purpose was to confirm whether hysteroscopy could be a risk factor of the tumor stage, recurrence and survival rate of endometrial cancer. METHODS: This multicenter retrospective study included all consecutive patients who had endometrial carcinoma diagnosed preoperatively with hysteroscopy and directed endometrial biopsy (HSC, group A) and dilatation and curettage (D&C, group B) between February 2014 and December 2018 at the Fujian Provincial, China. We compared the demographic feature, clinical characteristics and prognosis between the two groups. RESULTS: A total of 429 patients were included in the study (Group A, n = 77; Group B, n = 352). There was no significant difference between their baseline characteristics [including age, BMI, histological type and International Federation of Gynecology and Obstetrics (FIGO) stage]. By comparing several pathological conditions that may affect prognosis, there were no significant differences between the two groups in the peritoneal cytology, depth of myometrial invasion, the positivity of lymph nodes, lymphovascular space invasion and paraaortic lymph node dissection. Finally, no significant difference was found between the two groups in overall survival (OS) (P = 0.189) or recurrence free survival (RFS) (P = 0.787). CONCLUSION: Under certain inflation pressure and distension medium, hysteroscopic examination and lesion biopsy ensure the safety and have no adverse effects on prognosis compared to conventional curettage.
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spelling pubmed-98686602023-01-24 Comparison of prognosis of patients with endometrial cancer after hysteroscopy versus dilatation and curettage: A multicenter retrospective study Liu, Shihuang Zhen, Lan Zhang, Shaoyu Cai, Yurong Lin, Yanying Chen, Fulian Li, Xiaowen You, Qianru Lai, Xiaohong Lai, Hangbo Zheng, Xiangqin Yi, Huan Front Med (Lausanne) Medicine INTRODUCTION: Hysteroscopy is a useful procedure for diagnosing endometrial cancer. There is controversy regarding whether hysteroscopy affects the prognosis of endometrial cancer by prompting cancer cell into intraperitoneal dissemination. Our purpose was to confirm whether hysteroscopy could be a risk factor of the tumor stage, recurrence and survival rate of endometrial cancer. METHODS: This multicenter retrospective study included all consecutive patients who had endometrial carcinoma diagnosed preoperatively with hysteroscopy and directed endometrial biopsy (HSC, group A) and dilatation and curettage (D&C, group B) between February 2014 and December 2018 at the Fujian Provincial, China. We compared the demographic feature, clinical characteristics and prognosis between the two groups. RESULTS: A total of 429 patients were included in the study (Group A, n = 77; Group B, n = 352). There was no significant difference between their baseline characteristics [including age, BMI, histological type and International Federation of Gynecology and Obstetrics (FIGO) stage]. By comparing several pathological conditions that may affect prognosis, there were no significant differences between the two groups in the peritoneal cytology, depth of myometrial invasion, the positivity of lymph nodes, lymphovascular space invasion and paraaortic lymph node dissection. Finally, no significant difference was found between the two groups in overall survival (OS) (P = 0.189) or recurrence free survival (RFS) (P = 0.787). CONCLUSION: Under certain inflation pressure and distension medium, hysteroscopic examination and lesion biopsy ensure the safety and have no adverse effects on prognosis compared to conventional curettage. Frontiers Media S.A. 2023-01-09 /pmc/articles/PMC9868660/ /pubmed/36698830 http://dx.doi.org/10.3389/fmed.2022.1097133 Text en Copyright © 2023 Liu, Zhen, Zhang, Cai, Lin, Chen, Li, You, Lai, Lai, Zheng and Yi. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Liu, Shihuang
Zhen, Lan
Zhang, Shaoyu
Cai, Yurong
Lin, Yanying
Chen, Fulian
Li, Xiaowen
You, Qianru
Lai, Xiaohong
Lai, Hangbo
Zheng, Xiangqin
Yi, Huan
Comparison of prognosis of patients with endometrial cancer after hysteroscopy versus dilatation and curettage: A multicenter retrospective study
title Comparison of prognosis of patients with endometrial cancer after hysteroscopy versus dilatation and curettage: A multicenter retrospective study
title_full Comparison of prognosis of patients with endometrial cancer after hysteroscopy versus dilatation and curettage: A multicenter retrospective study
title_fullStr Comparison of prognosis of patients with endometrial cancer after hysteroscopy versus dilatation and curettage: A multicenter retrospective study
title_full_unstemmed Comparison of prognosis of patients with endometrial cancer after hysteroscopy versus dilatation and curettage: A multicenter retrospective study
title_short Comparison of prognosis of patients with endometrial cancer after hysteroscopy versus dilatation and curettage: A multicenter retrospective study
title_sort comparison of prognosis of patients with endometrial cancer after hysteroscopy versus dilatation and curettage: a multicenter retrospective study
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868660/
https://www.ncbi.nlm.nih.gov/pubmed/36698830
http://dx.doi.org/10.3389/fmed.2022.1097133
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