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1,4-dihydroxy quininib modulates the secretome of uveal melanoma tumour explants and a marker of oxidative phosphorylation in a metastatic xenograft model

Uveal melanoma (UM) is an intraocular cancer with propensity for liver metastases. The median overall survival (OS) for metastatic UM (MUM) is 1.07 years, with a reported range of 0.84–1.34. In primary UM, high cysteinyl leukotriene receptor 1 (CysLT(1)) expression associates with poor outcomes. Cys...

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Detalles Bibliográficos
Autores principales:	Slater, Kayleigh, Bosch, Rosa, Smith, Kaelin Francis, Jahangir, Chowdhury Arif, Garcia-Mulero, Sandra, Rahman, Arman, O’Connell, Fiona, Piulats, Josep M., O’Neill, Valerie, Horgan, Noel, Coupland, Sarah E., O’Sullivan, Jacintha, Gallagher, William M., Villanueva, Alberto, Kennedy, Breandán N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868667/ https://www.ncbi.nlm.nih.gov/pubmed/36698840 http://dx.doi.org/10.3389/fmed.2022.1036322

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