Hepatitis B Virus Utilizes a Retrograde Trafficking Route via the Trans-Golgi Network to Avoid Lysosomal Degradation

BACKGROUND & AIMS: Hepatitis B virus (HBV) infection is difficult to cure owing to the persistence of covalently closed circular viral DNA (cccDNA). We performed single-cell transcriptome analysis of newly established HBV-positive and HBV-negative hepatocellular carcinoma cell lines and found th...

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Detalles Bibliográficos
Autores principales: Li, Ying-Yi, Kuroki, Kazuyuki, Shimakami, Tetsuro, Murai, Kazuhisa, Kawaguchi, Kazunori, Shirasaki, Takayoshi, Nio, Kouki, Sugimoto, Saiho, Nishikawa, Tomoki, Okada, Hikari, Orita, Noriaki, Takayama, Hideo, Wang, Ying, Thi Bich, Phuong Doan, Ishida, Astuya, Iwabuchi, Sadahiro, Hashimoto, Shinichi, Shimaoka, Takeshi, Tabata, Noriko, Watanabe-Takahashi, Miho, Nishikawa, Kiyotaka, Yanagawa, Hiroshi, Seiki, Motoharu, Matsushima, Kouji, Yamashita, Taro, Kaneko, Shuichi, Honda, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868690/
https://www.ncbi.nlm.nih.gov/pubmed/36270602
http://dx.doi.org/10.1016/j.jcmgh.2022.10.008

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