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Characterization and modeling of the serum concentration of osteocalcin in breeding sows and its interaction with biochemical indicators: A review

Adipose, muscle, and bone tissues modulate the metabolic state of mammals. However, the role of bone tissue as a metabolic state modulator in sows has not been studied. During the gestation–lactation transition, sows undergo metabolic adaptations to meet their nutritional requirements. Among these a...

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Autores principales: Ordaz, Gerardo, Rentería, José Antonio, Mariscal, Gerardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A periodical of the Network for the Veterinarians of Bangladesh (BDvetNET) 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868799/
https://www.ncbi.nlm.nih.gov/pubmed/36714515
http://dx.doi.org/10.5455/javar.2022.i633
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author Ordaz, Gerardo
Rentería, José Antonio
Mariscal, Gerardo
author_facet Ordaz, Gerardo
Rentería, José Antonio
Mariscal, Gerardo
author_sort Ordaz, Gerardo
collection PubMed
description Adipose, muscle, and bone tissues modulate the metabolic state of mammals. However, the role of bone tissue as a metabolic state modulator in sows has not been studied. During the gestation–lactation transition, sows undergo metabolic adaptations to meet their nutritional requirements. Among these adaptations, bone remodeling is characterized by the synthesis and inhibition of hormones that participate, together with hormones from other tissues, in fetal development and lactogenesis. Osteocalcin is a hormone synthesized by the bone tissue which has been associated in different biological models with the improvement of the metabolic state. However, in sows, published results on the concentration of osteocalcin are scarce, and its concentration throughout the reproductive cycle is unknown. Therefore, with information from published trials on the measurement of serum osteocalcin, a structured review was conducted under the following objectives: (1) to review the promising effect of osteocalcin on energy metabolism in different models and (2) to characterize and model the serum concentrations of osteocalcin during the reproductive cycle of the sow. According to the review, the results obtained for humans and other animal models suggest that osteocalcin regulates energy metabolism, which has been associated with the need for integrated metabolism to cope with the metabolic demand during gestation and lactation in mammals. If these effects are significant in the sow, current recommendations for dietary balance should be reconsidered, particularly during the gestation–lactation transition period. According to mathematical modeling, it was the period in which the lowest concentration of osteocalcin was found.
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spelling pubmed-98687992023-01-26 Characterization and modeling of the serum concentration of osteocalcin in breeding sows and its interaction with biochemical indicators: A review Ordaz, Gerardo Rentería, José Antonio Mariscal, Gerardo J Adv Vet Anim Res Original Article Adipose, muscle, and bone tissues modulate the metabolic state of mammals. However, the role of bone tissue as a metabolic state modulator in sows has not been studied. During the gestation–lactation transition, sows undergo metabolic adaptations to meet their nutritional requirements. Among these adaptations, bone remodeling is characterized by the synthesis and inhibition of hormones that participate, together with hormones from other tissues, in fetal development and lactogenesis. Osteocalcin is a hormone synthesized by the bone tissue which has been associated in different biological models with the improvement of the metabolic state. However, in sows, published results on the concentration of osteocalcin are scarce, and its concentration throughout the reproductive cycle is unknown. Therefore, with information from published trials on the measurement of serum osteocalcin, a structured review was conducted under the following objectives: (1) to review the promising effect of osteocalcin on energy metabolism in different models and (2) to characterize and model the serum concentrations of osteocalcin during the reproductive cycle of the sow. According to the review, the results obtained for humans and other animal models suggest that osteocalcin regulates energy metabolism, which has been associated with the need for integrated metabolism to cope with the metabolic demand during gestation and lactation in mammals. If these effects are significant in the sow, current recommendations for dietary balance should be reconsidered, particularly during the gestation–lactation transition period. According to mathematical modeling, it was the period in which the lowest concentration of osteocalcin was found. A periodical of the Network for the Veterinarians of Bangladesh (BDvetNET) 2022-12-31 /pmc/articles/PMC9868799/ /pubmed/36714515 http://dx.doi.org/10.5455/javar.2022.i633 Text en Copyright: © Journal of Advanced Veterinary and Animal Research https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) )
spellingShingle Original Article
Ordaz, Gerardo
Rentería, José Antonio
Mariscal, Gerardo
Characterization and modeling of the serum concentration of osteocalcin in breeding sows and its interaction with biochemical indicators: A review
title Characterization and modeling of the serum concentration of osteocalcin in breeding sows and its interaction with biochemical indicators: A review
title_full Characterization and modeling of the serum concentration of osteocalcin in breeding sows and its interaction with biochemical indicators: A review
title_fullStr Characterization and modeling of the serum concentration of osteocalcin in breeding sows and its interaction with biochemical indicators: A review
title_full_unstemmed Characterization and modeling of the serum concentration of osteocalcin in breeding sows and its interaction with biochemical indicators: A review
title_short Characterization and modeling of the serum concentration of osteocalcin in breeding sows and its interaction with biochemical indicators: A review
title_sort characterization and modeling of the serum concentration of osteocalcin in breeding sows and its interaction with biochemical indicators: a review
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868799/
https://www.ncbi.nlm.nih.gov/pubmed/36714515
http://dx.doi.org/10.5455/javar.2022.i633
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