S100A8 alarmin supports IL-6 and metalloproteinase-9 production by fibroblasts in the synovial microenvironment of peripheral spondyloarthritis

INTRODUCTION: Spondyloarthritis (SpA) is a common autoinflammatory disease. S100A8/ S100A9 alarmin is strongly expressed in the synovial sublining layers of psoriatic arthritis. S100A8/ S100A9 is the most abundant protein in rheumatoid arthritis synovial fluid (SF) and has a key role in promoting IL...

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Detalles Bibliográficos
Autores principales: Arias, José L., Funes, Samanta C., Blas, Rodrigo, Callegari, Eduardo, Eliçabe, Ricardo J., Páez, María D., Munarriz, Alicia, Pardo-Hidalgo, Rodolfo, Tamashiro, Héctor, Di Genaro, María S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868917/
https://www.ncbi.nlm.nih.gov/pubmed/36700196
http://dx.doi.org/10.3389/fimmu.2022.1077914

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