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Machine learning in the estimation of CRISPR-Cas9 cleavage sites for plant system

CRISPR-Cas9 system is one of the recent most used genome editing techniques. Despite having a high capacity to alter the precise target genes and genomic regions that the planned guide RNA (or sgRNA) complements, the off-target effect still exists. But there are already machine learning algorithms f...

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Detalles Bibliográficos
Autores principales: Das, Jutan, Kumar, Sanjeev, Mishra, Dwijesh Chandra, Chaturvedi, Krishna Kumar, Paul, Ranjit Kumar, Kairi, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9868961/
https://www.ncbi.nlm.nih.gov/pubmed/36699447
http://dx.doi.org/10.3389/fgene.2022.1085332