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Oncogenic ERRB2 signals through the AP-1 transcription factor to control mesenchymal-like properties of oesophageal adenocarcinoma
Oesophageal adenocarcinoma (OAC) is a deadly disease with poor survival statistics and few targeted therapies available. One of the most common molecular aberrations in OAC is amplification or activation of the gene encoding the receptor tyrosine kinase ERBB2, and ERBB2 is targeted in the clinic for...
Autores principales: | Ogden, Samuel, Ahmed, Ibrahim, Yang, Shen-Hsi, Fullwood, Paul, Francavilla, Chiara, Sharrocks, Andrew D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869078/ https://www.ncbi.nlm.nih.gov/pubmed/36694726 http://dx.doi.org/10.1093/narcan/zcad001 |
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