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Novel heterozygous mutation in alpha-2-macroglobulin (A2M) suppressing the binding of amyloid-β (Aβ)

INTRODUCTION: Many studies have suggested that the alpha-2-macroglobulin (A2M) gene may be involved in the pathogenesis of Alzheimer's disease (AD). A2M encoded by the A2M gene can specifically bind to the β-amyloid peptide and prevent fiber formation. METHODS: The patient in this study had pro...

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Detalles Bibliográficos
Autores principales:	Qiu, Guozhen, Cao, Liming, Chen, Yong-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869127/ https://www.ncbi.nlm.nih.gov/pubmed/36698894 http://dx.doi.org/10.3389/fneur.2022.1090900

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