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Sensory impairment and cognitive decline among older adults: An analysis of mediation and moderation effects of loneliness

BACKGROUND: Multiple studies have reported that hearing and vision impairment are linked to cognitive decline. Yet little is known about factors that may influence the association between sensory impairment and cognitive decline. This study examined if loneliness mediates or moderates the impact of...

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Autores principales: Ge, Shaoqing, Pan, Wei, Wu, Bei, Plassman, Brenda L., Dong, XinQi, McConnell, Eleanor S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869267/
https://www.ncbi.nlm.nih.gov/pubmed/36699540
http://dx.doi.org/10.3389/fnins.2022.1092297
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author Ge, Shaoqing
Pan, Wei
Wu, Bei
Plassman, Brenda L.
Dong, XinQi
McConnell, Eleanor S.
author_facet Ge, Shaoqing
Pan, Wei
Wu, Bei
Plassman, Brenda L.
Dong, XinQi
McConnell, Eleanor S.
author_sort Ge, Shaoqing
collection PubMed
description BACKGROUND: Multiple studies have reported that hearing and vision impairment are linked to cognitive decline. Yet little is known about factors that may influence the association between sensory impairment and cognitive decline. This study examined if loneliness mediates or moderates the impact of sensory impairment on cognitive decline as individuals age. METHODS: This was a longitudinal study using data from the Health and Retirement Study (HRS) and The Aging, Demographics, and Memory Study (ADAMS) (N = 243). We used one timepoint of hearing and vision (ADAMS 2006–2008), one timepoint of loneliness (HRS 2006–2008), and five waves of cognition (HRS 2006–2014). Hearing impairment was defined by an inability to hear pure-tone stimuli of 25 dB at frequencies between 0.5 and 4.0 kHz in either ear. Visual impairment was defined as having corrected binocular vision worse than 20/40. Longitudinal parallel-process (LPP) analysis was conducted at a significance level of α = 0.05 (one-tailed). RESULTS: Loneliness moderated but did not mediate the association between visual impairment and the rate of cognitive decline (standardized β =−0.108, p < 0.05). No moderation or mediation effect of loneliness was found for the association between hearing impairment and cognitive decline. Both vision and hearing impairment were significantly associated with increased severity of loneliness. CONCLUSION: Visual impairment combined with an elevated level of loneliness may produce a more synergistic, deleterious impact on older adults’ cognitive function than visual impairment alone. This study highlights the importance of promoting a healthy social and psychological status for older adults with sensory impairment.
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spelling pubmed-98692672023-01-24 Sensory impairment and cognitive decline among older adults: An analysis of mediation and moderation effects of loneliness Ge, Shaoqing Pan, Wei Wu, Bei Plassman, Brenda L. Dong, XinQi McConnell, Eleanor S. Front Neurosci Neuroscience BACKGROUND: Multiple studies have reported that hearing and vision impairment are linked to cognitive decline. Yet little is known about factors that may influence the association between sensory impairment and cognitive decline. This study examined if loneliness mediates or moderates the impact of sensory impairment on cognitive decline as individuals age. METHODS: This was a longitudinal study using data from the Health and Retirement Study (HRS) and The Aging, Demographics, and Memory Study (ADAMS) (N = 243). We used one timepoint of hearing and vision (ADAMS 2006–2008), one timepoint of loneliness (HRS 2006–2008), and five waves of cognition (HRS 2006–2014). Hearing impairment was defined by an inability to hear pure-tone stimuli of 25 dB at frequencies between 0.5 and 4.0 kHz in either ear. Visual impairment was defined as having corrected binocular vision worse than 20/40. Longitudinal parallel-process (LPP) analysis was conducted at a significance level of α = 0.05 (one-tailed). RESULTS: Loneliness moderated but did not mediate the association between visual impairment and the rate of cognitive decline (standardized β =−0.108, p < 0.05). No moderation or mediation effect of loneliness was found for the association between hearing impairment and cognitive decline. Both vision and hearing impairment were significantly associated with increased severity of loneliness. CONCLUSION: Visual impairment combined with an elevated level of loneliness may produce a more synergistic, deleterious impact on older adults’ cognitive function than visual impairment alone. This study highlights the importance of promoting a healthy social and psychological status for older adults with sensory impairment. Frontiers Media S.A. 2023-01-09 /pmc/articles/PMC9869267/ /pubmed/36699540 http://dx.doi.org/10.3389/fnins.2022.1092297 Text en Copyright © 2023 Ge, Pan, Wu, Plassman, Dong and McConnell. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Ge, Shaoqing
Pan, Wei
Wu, Bei
Plassman, Brenda L.
Dong, XinQi
McConnell, Eleanor S.
Sensory impairment and cognitive decline among older adults: An analysis of mediation and moderation effects of loneliness
title Sensory impairment and cognitive decline among older adults: An analysis of mediation and moderation effects of loneliness
title_full Sensory impairment and cognitive decline among older adults: An analysis of mediation and moderation effects of loneliness
title_fullStr Sensory impairment and cognitive decline among older adults: An analysis of mediation and moderation effects of loneliness
title_full_unstemmed Sensory impairment and cognitive decline among older adults: An analysis of mediation and moderation effects of loneliness
title_short Sensory impairment and cognitive decline among older adults: An analysis of mediation and moderation effects of loneliness
title_sort sensory impairment and cognitive decline among older adults: an analysis of mediation and moderation effects of loneliness
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869267/
https://www.ncbi.nlm.nih.gov/pubmed/36699540
http://dx.doi.org/10.3389/fnins.2022.1092297
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