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Outcomes in Patients Undergoing Surgical Aortic Valve Replacement With vs Without a Preoperative Heart Team Assessment

BACKGROUND: This study sought to compare characteristics and outcomes of patients who underwent surgical aortic valve replacement (SAVR) after being referred to a heart team (HT), to those of patients referred directly for SAVR. METHODS: An analysis of patients who underwent SAVR from 2015 to 2020 w...

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Autores principales: Rodighiero, Julia, Alakhtar, Ali M., Baker, Nouf, Zgheib, Ali, de Varennes, Benoit, Lachapelle, Kevin, Cecere, Renzo, Ergina, Patrick, Tchervenkov, Christo, Shum-Tim, Dominique, Martucci, Giuseppe, Piazza, Nicolo, Afilalo, Jonathan, Spaziano, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869348/
https://www.ncbi.nlm.nih.gov/pubmed/36700182
http://dx.doi.org/10.1016/j.cjco.2022.10.003
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author Rodighiero, Julia
Alakhtar, Ali M.
Baker, Nouf
Zgheib, Ali
de Varennes, Benoit
Lachapelle, Kevin
Cecere, Renzo
Ergina, Patrick
Tchervenkov, Christo
Shum-Tim, Dominique
Martucci, Giuseppe
Piazza, Nicolo
Afilalo, Jonathan
Spaziano, Marco
author_facet Rodighiero, Julia
Alakhtar, Ali M.
Baker, Nouf
Zgheib, Ali
de Varennes, Benoit
Lachapelle, Kevin
Cecere, Renzo
Ergina, Patrick
Tchervenkov, Christo
Shum-Tim, Dominique
Martucci, Giuseppe
Piazza, Nicolo
Afilalo, Jonathan
Spaziano, Marco
author_sort Rodighiero, Julia
collection PubMed
description BACKGROUND: This study sought to compare characteristics and outcomes of patients who underwent surgical aortic valve replacement (SAVR) after being referred to a heart team (HT), to those of patients referred directly for SAVR. METHODS: An analysis of patients who underwent SAVR from 2015 to 2020 was conducted. Patients were categorized into 3 groups, as follows: (i) H-HT: patients referred to the HT from 2015 to 2017 (historical cohort); (ii) C-HT: patients referred to the HT from 2018 to 2020 (contemporary cohort); and (iii) No-HT: patients referred directly to cardiac surgery from 2018 to 2020. Two subanalyses were performed: H-HT vs C-HT patients, and C-HT vs No-HT patients. The primary outcome was a composite of in-hospital mortality, prolonged intubation, reoperation, sternal wound infection, and stroke. RESULTS: This study consisted of 288 patients, distributed as follows: H-HT (n = 45); C-HT (n = 51); and No-HT (n = 192). The mean ages of H-HT, C-HT, and No-HT patients was 76.3 ± 6.9 years, 73.3 ± 7.6 years, and 69.6 ± 9.7 years, respectively (P = 0.0001). H-HT, C-HT, and No-HT patients had average Society of Thoracic Surgeons scores of 4.8 ± 2.2, 3.2 ± 1.6, and 4.2 ± 2 (P = 0.002), respectively. The composite outcome rate was more than 5 times higher among H-HT patients compared to that among the C-HT patients (20.0 vs 3.9%, P = 0.02), and was numerically higher in No-HT compared to C-HT patients (13.0 vs 3.9%, P = 0.07). CONCLUSIONS: Referral to an HT appears to be primarily driven by higher chronological age rather than overall risk profile. Patients assessed by the HT prior to undergoing SAVR have a low incidence of complications, comparable to that among patients referred directly to cardiac surgery.
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spelling pubmed-98693482023-01-24 Outcomes in Patients Undergoing Surgical Aortic Valve Replacement With vs Without a Preoperative Heart Team Assessment Rodighiero, Julia Alakhtar, Ali M. Baker, Nouf Zgheib, Ali de Varennes, Benoit Lachapelle, Kevin Cecere, Renzo Ergina, Patrick Tchervenkov, Christo Shum-Tim, Dominique Martucci, Giuseppe Piazza, Nicolo Afilalo, Jonathan Spaziano, Marco CJC Open Original Article BACKGROUND: This study sought to compare characteristics and outcomes of patients who underwent surgical aortic valve replacement (SAVR) after being referred to a heart team (HT), to those of patients referred directly for SAVR. METHODS: An analysis of patients who underwent SAVR from 2015 to 2020 was conducted. Patients were categorized into 3 groups, as follows: (i) H-HT: patients referred to the HT from 2015 to 2017 (historical cohort); (ii) C-HT: patients referred to the HT from 2018 to 2020 (contemporary cohort); and (iii) No-HT: patients referred directly to cardiac surgery from 2018 to 2020. Two subanalyses were performed: H-HT vs C-HT patients, and C-HT vs No-HT patients. The primary outcome was a composite of in-hospital mortality, prolonged intubation, reoperation, sternal wound infection, and stroke. RESULTS: This study consisted of 288 patients, distributed as follows: H-HT (n = 45); C-HT (n = 51); and No-HT (n = 192). The mean ages of H-HT, C-HT, and No-HT patients was 76.3 ± 6.9 years, 73.3 ± 7.6 years, and 69.6 ± 9.7 years, respectively (P = 0.0001). H-HT, C-HT, and No-HT patients had average Society of Thoracic Surgeons scores of 4.8 ± 2.2, 3.2 ± 1.6, and 4.2 ± 2 (P = 0.002), respectively. The composite outcome rate was more than 5 times higher among H-HT patients compared to that among the C-HT patients (20.0 vs 3.9%, P = 0.02), and was numerically higher in No-HT compared to C-HT patients (13.0 vs 3.9%, P = 0.07). CONCLUSIONS: Referral to an HT appears to be primarily driven by higher chronological age rather than overall risk profile. Patients assessed by the HT prior to undergoing SAVR have a low incidence of complications, comparable to that among patients referred directly to cardiac surgery. Elsevier 2022-10-13 /pmc/articles/PMC9869348/ /pubmed/36700182 http://dx.doi.org/10.1016/j.cjco.2022.10.003 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Rodighiero, Julia
Alakhtar, Ali M.
Baker, Nouf
Zgheib, Ali
de Varennes, Benoit
Lachapelle, Kevin
Cecere, Renzo
Ergina, Patrick
Tchervenkov, Christo
Shum-Tim, Dominique
Martucci, Giuseppe
Piazza, Nicolo
Afilalo, Jonathan
Spaziano, Marco
Outcomes in Patients Undergoing Surgical Aortic Valve Replacement With vs Without a Preoperative Heart Team Assessment
title Outcomes in Patients Undergoing Surgical Aortic Valve Replacement With vs Without a Preoperative Heart Team Assessment
title_full Outcomes in Patients Undergoing Surgical Aortic Valve Replacement With vs Without a Preoperative Heart Team Assessment
title_fullStr Outcomes in Patients Undergoing Surgical Aortic Valve Replacement With vs Without a Preoperative Heart Team Assessment
title_full_unstemmed Outcomes in Patients Undergoing Surgical Aortic Valve Replacement With vs Without a Preoperative Heart Team Assessment
title_short Outcomes in Patients Undergoing Surgical Aortic Valve Replacement With vs Without a Preoperative Heart Team Assessment
title_sort outcomes in patients undergoing surgical aortic valve replacement with vs without a preoperative heart team assessment
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869348/
https://www.ncbi.nlm.nih.gov/pubmed/36700182
http://dx.doi.org/10.1016/j.cjco.2022.10.003
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