A novel polypeptide encoded by the circular RNA ZKSCAN1 suppresses HCC via degradation of mTOR

BACKGROUND: hsa_circ_0001727 (circZKSCAN1) has been reported to be a tumor-associated circRNA by sponging microRNAs. Intriguingly, we found that circZKSCAN1 encoded a secretory peptide (circZKSaa) in the liver. The present study aims to elucidate the potential role and molecular mechanism of circZKS...

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Detalles Bibliográficos
Autores principales: Song, Runjie, Ma, Shuoqian, Xu, Jiajia, Ren, Xin, Guo, Peilan, Liu, Huijiao, Li, Peng, Yin, Fan, Liu, Mei, Wang, Qiang, Yu, Lei, Liu, Jiali, Duan, Binwei, Rahman, Nafis A., Wołczyński, Sławomir, Li, Guangming, Li, Xiangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869513/
https://www.ncbi.nlm.nih.gov/pubmed/36691031
http://dx.doi.org/10.1186/s12943-023-01719-9

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