Ubiquitin protein E3 ligase ASB9 suppresses proliferation and promotes apoptosis in human spermatogonial stem cell line by inducing HIF1AN degradation

BACKGROUND: Spermatogonial stem cells (SSCs) are critical for sustaining spermatogenesis. Even though several regulators of SSC have been identified in rodents, the regulatory mechanism of SSC in humans has yet to be discovered. METHODS: To explore the regulatory mechanisms of human SSCs, we analyze...

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Detalles Bibliográficos
Autores principales: Li, Ning, Zhou, Qianyin, Yi, Zhang, Zhang, Huan, Zhou, Dai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869568/
https://www.ncbi.nlm.nih.gov/pubmed/36683111
http://dx.doi.org/10.1186/s40659-023-00413-w

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