HIF1A-dependent induction of alveolar epithelial PFKFB3 dampens acute lung injury

Acute lung injury (ALI) is a severe form of lung inflammation causing acute respiratory distress syndrome in patients. ALI pathogenesis is closely linked to uncontrolled alveolar inflammation. We hypothesize that specific enzymes of the glycolytic pathway could function as key regulators of alveolar...

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Detalles Bibliográficos
Autores principales: Vohwinkel, Christine U., Burns, Nana, Coit, Ethan, Yuan, Xiaoyi, Vladar, Eszter K., Sul, Christina, Schmidt, Eric P., Carmeliet, Peter, Stenmark, Kurt, Nozik, Eva S., Tuder, Rubin M., Eltzschig, Holger K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869967/
https://www.ncbi.nlm.nih.gov/pubmed/36326834
http://dx.doi.org/10.1172/jci.insight.157855

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