NKG2D receptor activation drives primary graft dysfunction severity and poor lung transplantation outcomes

Clinical outcomes after lung transplantation, a life-saving therapy for patients with end-stage lung diseases, are limited by primary graft dysfunction (PGD). PGD is an early form of acute lung injury with no specific pharmacologic therapies. Here, we present a large multicenter study of plasma and...

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Detalles Bibliográficos
Autores principales: Calabrese, Daniel R., Tsao, Tasha, Magnen, Mélia, Valet, Colin, Gao, Ying, Mallavia, Beñat, Tian, Jennifer J., Aminian, Emily A., Wang, Kristin M., Shemesh, Avishai, Punzalan, Elman B., Sarma, Aartik, Calfee, Carolyn S., Christenson, Stephanie A., Langelier, Charles R., Hays, Steven R., Golden, Jeffrey A., Leard, Lorriana E., Kleinhenz, Mary Ellen, Kolaitis, Nicholas A., Shah, Rupal, Venado, Aida, Lanier, Lewis L., Greenland, John R., Sayah, David M., Ardehali, Abbas, Kukreja, Jasleen, Weigt, S. Samuel, Belperio, John A., Singer, Jonathan P., Looney, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9869973/
https://www.ncbi.nlm.nih.gov/pubmed/36346670
http://dx.doi.org/10.1172/jci.insight.164603

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