Cargando…

Synthesis and structure–activity relationships of pyrazole-based inhibitors of meprin α and β

Targeting metalloproteinases has been in the focus of drug design for a long time. However, meprin α and β emerged as potential drug targets just recently and are linked to several diseases with different pathological background. Nevertheless, the validation of meprins as suitable drug targets still...

Descripción completa

Detalles Bibliográficos
Autores principales: Tan, Kathrin, Jäger, Christian, Geissler, Stefanie, Schlenzig, Dagmar, Buchholz, Mirko, Ramsbeck, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870012/
https://www.ncbi.nlm.nih.gov/pubmed/36661029
http://dx.doi.org/10.1080/14756366.2023.2165648