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Synthesis and structure–activity relationships of pyrazole-based inhibitors of meprin α and β
Targeting metalloproteinases has been in the focus of drug design for a long time. However, meprin α and β emerged as potential drug targets just recently and are linked to several diseases with different pathological background. Nevertheless, the validation of meprins as suitable drug targets still...
Autores principales: | Tan, Kathrin, Jäger, Christian, Geissler, Stefanie, Schlenzig, Dagmar, Buchholz, Mirko, Ramsbeck, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870012/ https://www.ncbi.nlm.nih.gov/pubmed/36661029 http://dx.doi.org/10.1080/14756366.2023.2165648 |
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