Genome-wide analyses of platinum-induced ototoxicity in childhood cancer patients: Results of GO-CAT and United Kingdom MAGIC consortia

Hearing loss (ototoxicity) is a major adverse effect of cisplatin and carboplatin chemotherapy. The aim of this study is to identify novel genetic variants that play a role in platinum-induced ototoxicity. Therefore, a genome-wide association study was performed in the Genetics of Childhood Cancer T...

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Detalles Bibliográficos
Autores principales: Hurkmans, Evelien G. E., Klumpers, Marije J., Dello Russo, Cinzia, De Witte, Ward, Guchelaar, Henk-Jan, Gelderblom, Hans, Cleton-Jansen, Anne-Marie, Vermeulen, Sita H., Kaal, Suzanne, van der Graaf, Winette T. A., Flucke, Uta, Gidding, Corrie E. M., Schreuder, Hendrik W. B., de Bont, Eveline S. J. M., Caron, Huib N., Gattuso, Giovanna, Schiavello, Elisabetta, Terenziani, Monica, Massimino, Maura, McCowage, Geoff, Nagabushan, Sumanth, Limaye, Anuja, Rose, Victoria, Catchpoole, Daniel, Jorgensen, Andrea L., Barton, Christopher, Delaney, Lucy, Hawcutt, Daniel B., Pirmohamed, Munir, Pizer, Barry, Coenen, Marieke J. H., te Loo, D. Maroeska W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870026/
https://www.ncbi.nlm.nih.gov/pubmed/36699085
http://dx.doi.org/10.3389/fphar.2022.980309

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