Mucociliary transport deficiency and disease progression in Syrian hamsters with SARS-CoV-2 infection

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Substantial clinical evidence supports the notion that ciliary function in the airways is important in COVID-19 pathogenesis. Although ciliary damage has been observed in both in vitro and in vivo models, the extent or nature of impairment of mucociliary transport (MCT) in in vivo models remains unk...

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Detalles Bibliográficos
Autores principales: Li, Qian, Vijaykumar, Kadambari, Phillips, Scott E., Hussain, Shah S., Huynh, Nha V., Fernandez-Petty, Courtney M., Lever, Jacelyn E. Peabody, Foote, Jeremy B., Ren, Janna, Campos-Gómez, Javier, Daya, Farah Abou, Hubbs, Nathaniel W., Kim, Harrison, Onuoha, Ezinwanne, Boitet, Evan R., Fu, Lianwu, Leung, Hui Min, Yu, Linhui, Detchemendy, Thomas W., Schaefers, Levi T., Tipper, Jennifer L., Edwards, Lloyd J., Leal, Sixto M., Harrod, Kevin S., Tearney, Guillermo J., Rowe, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870055/
https://www.ncbi.nlm.nih.gov/pubmed/36625345
http://dx.doi.org/10.1172/jci.insight.163962
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