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CCL3 in the bone marrow microenvironment causes bone loss and bone marrow adiposity in aged mice

The central physiological role of the bone marrow renders bone marrow stromal cells (BMSCs) particularly sensitive to aging. With bone aging, BMSCs acquire a differentiation potential bias in favor of adipogenesis over osteogenesis, and the underlying molecular mechanisms remain unclear. Herein, we...

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Detalles Bibliográficos
Autores principales:	Yu, Degang, Zhang, Shuhong, Ma, Chao, Huang, Sen, Xu, Long, Liang, Jun, Li, Huiwu, Fan, Qiming, Liu, Guangwang, Zhai, Zanjing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870077/ https://www.ncbi.nlm.nih.gov/pubmed/36378535 http://dx.doi.org/10.1172/jci.insight.159107

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