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Longitudinal single-cell analysis of SARS-CoV-2–reactive B cells uncovers persistence of early-formed, antigen-specific clones

Understanding persistence and evolution of B cell clones after COVID-19 infection and vaccination is crucial for predicting responses against emerging viral variants and optimizing vaccines. Here, we collected longitudinal samples from patients with severe COVID-19 every third to seventh day during...

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Detalles Bibliográficos
Autores principales: Scharf, Lydia, Axelsson, Hannes, Emmanouilidi, Aikaterini, Mathew, Nimitha R., Sheward, Daniel J., Leach, Susannah, Isakson, Pauline, Smirnov, Ilya V., Marklund, Emelie, Miron, Nicolae, Andersson, Lars-Magnus, Gisslén, Magnus, Murrell, Ben, Lundgren, Anna, Bemark, Mats, Angeletti, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870078/
https://www.ncbi.nlm.nih.gov/pubmed/36445762
http://dx.doi.org/10.1172/jci.insight.165299