NF-κB represses retinoic acid receptor–mediated GPRC5A transactivation in lung epithelial cells to promote neoplasia

Chronic inflammation is associated with lung tumorigenesis, in which NF-κB–mediated epigenetic regulation plays a critical role. Lung tumor suppressor G protein–coupled receptor, family C, member 5A (GPRC5A), is repressed in most non–small cell lung cancer (NSCLC); however, the mechanisms remain unc...

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Detalles Bibliográficos
Autores principales: Song, Hongyong, Ye, Xiaofeng, Liao, Yueling, Zhang, Siwei, Xu, Dongliang, Zhong, Shuangshuang, Jing, Bo, Wang, Tong, Sun, Beibei, Xu, Jianhua, Guo, Wenzheng, Li, Kaimi, Hu, Min, Kuang, Yanbin, Ling, Jing, Zhang, Tuo, Wu, Yadi, Du, Jing, Yao, Feng, Chin, Y. Eugene, Wang, Qi, Zhou, Binhua P., Deng, Jiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870083/
https://www.ncbi.nlm.nih.gov/pubmed/36413416
http://dx.doi.org/10.1172/jci.insight.153976

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