Minocycline-induced disruption of the intestinal FXR/FGF15 axis impairs osteogenesis in mice

Antibiotic-induced shifts in the indigenous gut microbiota influence normal skeletal maturation. Current theory implies that gut microbiota actions on bone occur through a direct gut/bone signaling axis. However, our prior work supports that a gut/liver signaling axis contributes to gut microbiota e...

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Detalles Bibliográficos
Autores principales: Carson, Matthew D., Warner, Amy J., Hathaway-Schrader, Jessica D., Geiser, Vincenza L., Kim, Joseph, Gerasco, Joy E., Hill, William D., Lemasters, John J., Alekseyenko, Alexander V., Wu, Yongren, Yao, Hai, Aguirre, J. Ignacio, Westwater, Caroline, Novince, Chad M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870091/
https://www.ncbi.nlm.nih.gov/pubmed/36413391
http://dx.doi.org/10.1172/jci.insight.160578

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