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Circulating Tumor DNA Identifies Diverse Landscape of Acquired Resistance to Anti–Epidermal Growth Factor Receptor Therapy in Metastatic Colorectal Cancer

Anti–epidermal growth factor receptor (EGFR) antibodies are effective treatments for metastatic colorectal cancer. Improved understanding of acquired resistance mechanisms may facilitate circulating tumor DNA (ctDNA) monitoring, anti-EGFR rechallenge, and combinatorial strategies to delay resistance...

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Detalles Bibliográficos
Autores principales: Topham, James T., O'Callaghan, Chris J., Feilotter, Harriet, Kennecke, Hagen F., Lee, Young S., Li, Weimin, Banks, Kimberly C., Quinn, Katie, Renouf, Daniel J., Jonker, Derek J., Tu, Dongsheng, Chen, Eric X., Loree, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870216/
https://www.ncbi.nlm.nih.gov/pubmed/36007218
http://dx.doi.org/10.1200/JCO.22.00364

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