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Circulating Tumor DNA Identifies Diverse Landscape of Acquired Resistance to Anti–Epidermal Growth Factor Receptor Therapy in Metastatic Colorectal Cancer
Anti–epidermal growth factor receptor (EGFR) antibodies are effective treatments for metastatic colorectal cancer. Improved understanding of acquired resistance mechanisms may facilitate circulating tumor DNA (ctDNA) monitoring, anti-EGFR rechallenge, and combinatorial strategies to delay resistance...
Autores principales: | Topham, James T., O'Callaghan, Chris J., Feilotter, Harriet, Kennecke, Hagen F., Lee, Young S., Li, Weimin, Banks, Kimberly C., Quinn, Katie, Renouf, Daniel J., Jonker, Derek J., Tu, Dongsheng, Chen, Eric X., Loree, Jonathan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870216/ https://www.ncbi.nlm.nih.gov/pubmed/36007218 http://dx.doi.org/10.1200/JCO.22.00364 |
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