Cargando…

Effects of intestinal microbes on rheumatic diseases: A bibliometric analysis

BACKGROUND: Rheumatic diseases (RD) are a group of multi-system inflammatory autoimmune diseases whose causes are still under study. In the past few decades, researchers have found traces of the association between rheumatic diseases and intestinal microbiota, which can partially explain the pathoge...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Runzhi, Zhang, Mengyi, Lu, Yuwei, Xu, Dayuan, Liu, Yifan, Jin, Minghao, Xian, Shuyuan, Wang, Siqiao, Tong, Xirui, Lu, Jianyu, Zhang, Wei, Qian, Weijin, Tang, Jieling, Yang, Yiting, Lu, Bingnan, Chang, Zhengyan, Liu, Xin, Ji, Shizhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870327/
https://www.ncbi.nlm.nih.gov/pubmed/36699603
http://dx.doi.org/10.3389/fmicb.2022.1074003
_version_ 1784876952883036160
author Huang, Runzhi
Zhang, Mengyi
Lu, Yuwei
Xu, Dayuan
Liu, Yifan
Jin, Minghao
Xian, Shuyuan
Wang, Siqiao
Tong, Xirui
Lu, Jianyu
Zhang, Wei
Qian, Weijin
Tang, Jieling
Yang, Yiting
Lu, Bingnan
Chang, Zhengyan
Liu, Xin
Ji, Shizhao
author_facet Huang, Runzhi
Zhang, Mengyi
Lu, Yuwei
Xu, Dayuan
Liu, Yifan
Jin, Minghao
Xian, Shuyuan
Wang, Siqiao
Tong, Xirui
Lu, Jianyu
Zhang, Wei
Qian, Weijin
Tang, Jieling
Yang, Yiting
Lu, Bingnan
Chang, Zhengyan
Liu, Xin
Ji, Shizhao
author_sort Huang, Runzhi
collection PubMed
description BACKGROUND: Rheumatic diseases (RD) are a group of multi-system inflammatory autoimmune diseases whose causes are still under study. In the past few decades, researchers have found traces of the association between rheumatic diseases and intestinal microbiota, which can partially explain the pathogenesis of rheumatic diseases. We aimed to describe the research trend and main divisions on how gut flora interreacts with rheumatic diseases, and discussed about the possible clinical applications. METHODS: We analyzed bibliometric data from the Web of Science core collection (dated 15th May 2022). Biblioshiny R language software packages (bibliometrix) were used to obtain the annual publication and citations, core sources according to Bradford’s law, and country collaboration map. We designed and verified the keyword co-occurrence network and strategic diagram with the help of VOSviewer and CiteSpace, subdivided the research topic into several themes and identified research dimensions. The tables of most local cited documents and core sources were processed manually. Furthermore, the Altmetric Attention Score and the annual Altmetric Top 100 were applied to analyze the annual publication and citation. RESULTS: From a total of 541 documents, we found that the overall trend of annual publication and citation is increasing. The major research method is to compare the intestinal microbial composition of patients with certain rheumatic disease and that of the control group to determine microbial alterations related to the disease’s occurrence and development. According to Bradford’s law, the core sources are Arthritis and Rheumatology, Annals of the Rheumatic Diseases, Current Opinion in Rheumatology, Nutrients, Rheumatology, and Journal of Rheumatology. Since 1976, 101 countries or regions have participated in studies of rheumatology and intestinal microbes. The United States ranks at the top and has the broadest academic association with other countries. Five themes were identified, including the pivotal role of inflammation caused by intestinal bacteria in the rheumatic pathogenesis, the close relationship between rheumatic diseases and inflammatory bowel disease, immunoregulation mechanism as a mediator of the interaction between rheumatic diseases and gut flora, dysbiosis and decreased diversity in intestine of patients with rheumatic diseases, and the influence of oral flora on rheumatic diseases. Additionally, four research dimensions were identified, including pathology, treatment, disease, and experiments. CONCLUSION: Studies on rheumatic diseases and the intestinal microbiota are growing. Attention should be paid to the mechanism of their interaction, such as the microbe-immune-RD crosstalk. Hopefully, the research achievements can be applied to diseases’ prevention, diagnosis, and treatment, and our work can contribute to the readers’ future research.
format Online
Article
Text
id pubmed-9870327
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-98703272023-01-24 Effects of intestinal microbes on rheumatic diseases: A bibliometric analysis Huang, Runzhi Zhang, Mengyi Lu, Yuwei Xu, Dayuan Liu, Yifan Jin, Minghao Xian, Shuyuan Wang, Siqiao Tong, Xirui Lu, Jianyu Zhang, Wei Qian, Weijin Tang, Jieling Yang, Yiting Lu, Bingnan Chang, Zhengyan Liu, Xin Ji, Shizhao Front Microbiol Microbiology BACKGROUND: Rheumatic diseases (RD) are a group of multi-system inflammatory autoimmune diseases whose causes are still under study. In the past few decades, researchers have found traces of the association between rheumatic diseases and intestinal microbiota, which can partially explain the pathogenesis of rheumatic diseases. We aimed to describe the research trend and main divisions on how gut flora interreacts with rheumatic diseases, and discussed about the possible clinical applications. METHODS: We analyzed bibliometric data from the Web of Science core collection (dated 15th May 2022). Biblioshiny R language software packages (bibliometrix) were used to obtain the annual publication and citations, core sources according to Bradford’s law, and country collaboration map. We designed and verified the keyword co-occurrence network and strategic diagram with the help of VOSviewer and CiteSpace, subdivided the research topic into several themes and identified research dimensions. The tables of most local cited documents and core sources were processed manually. Furthermore, the Altmetric Attention Score and the annual Altmetric Top 100 were applied to analyze the annual publication and citation. RESULTS: From a total of 541 documents, we found that the overall trend of annual publication and citation is increasing. The major research method is to compare the intestinal microbial composition of patients with certain rheumatic disease and that of the control group to determine microbial alterations related to the disease’s occurrence and development. According to Bradford’s law, the core sources are Arthritis and Rheumatology, Annals of the Rheumatic Diseases, Current Opinion in Rheumatology, Nutrients, Rheumatology, and Journal of Rheumatology. Since 1976, 101 countries or regions have participated in studies of rheumatology and intestinal microbes. The United States ranks at the top and has the broadest academic association with other countries. Five themes were identified, including the pivotal role of inflammation caused by intestinal bacteria in the rheumatic pathogenesis, the close relationship between rheumatic diseases and inflammatory bowel disease, immunoregulation mechanism as a mediator of the interaction between rheumatic diseases and gut flora, dysbiosis and decreased diversity in intestine of patients with rheumatic diseases, and the influence of oral flora on rheumatic diseases. Additionally, four research dimensions were identified, including pathology, treatment, disease, and experiments. CONCLUSION: Studies on rheumatic diseases and the intestinal microbiota are growing. Attention should be paid to the mechanism of their interaction, such as the microbe-immune-RD crosstalk. Hopefully, the research achievements can be applied to diseases’ prevention, diagnosis, and treatment, and our work can contribute to the readers’ future research. Frontiers Media S.A. 2023-01-09 /pmc/articles/PMC9870327/ /pubmed/36699603 http://dx.doi.org/10.3389/fmicb.2022.1074003 Text en Copyright © 2023 Huang, Zhang, Lu, Xu, Liu, Jin, Xian, Wang, Tong, Lu, Zhang, Qian, Tang, Yang, Lu, Chang, Liu and Ji. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Huang, Runzhi
Zhang, Mengyi
Lu, Yuwei
Xu, Dayuan
Liu, Yifan
Jin, Minghao
Xian, Shuyuan
Wang, Siqiao
Tong, Xirui
Lu, Jianyu
Zhang, Wei
Qian, Weijin
Tang, Jieling
Yang, Yiting
Lu, Bingnan
Chang, Zhengyan
Liu, Xin
Ji, Shizhao
Effects of intestinal microbes on rheumatic diseases: A bibliometric analysis
title Effects of intestinal microbes on rheumatic diseases: A bibliometric analysis
title_full Effects of intestinal microbes on rheumatic diseases: A bibliometric analysis
title_fullStr Effects of intestinal microbes on rheumatic diseases: A bibliometric analysis
title_full_unstemmed Effects of intestinal microbes on rheumatic diseases: A bibliometric analysis
title_short Effects of intestinal microbes on rheumatic diseases: A bibliometric analysis
title_sort effects of intestinal microbes on rheumatic diseases: a bibliometric analysis
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870327/
https://www.ncbi.nlm.nih.gov/pubmed/36699603
http://dx.doi.org/10.3389/fmicb.2022.1074003
work_keys_str_mv AT huangrunzhi effectsofintestinalmicrobesonrheumaticdiseasesabibliometricanalysis
AT zhangmengyi effectsofintestinalmicrobesonrheumaticdiseasesabibliometricanalysis
AT luyuwei effectsofintestinalmicrobesonrheumaticdiseasesabibliometricanalysis
AT xudayuan effectsofintestinalmicrobesonrheumaticdiseasesabibliometricanalysis
AT liuyifan effectsofintestinalmicrobesonrheumaticdiseasesabibliometricanalysis
AT jinminghao effectsofintestinalmicrobesonrheumaticdiseasesabibliometricanalysis
AT xianshuyuan effectsofintestinalmicrobesonrheumaticdiseasesabibliometricanalysis
AT wangsiqiao effectsofintestinalmicrobesonrheumaticdiseasesabibliometricanalysis
AT tongxirui effectsofintestinalmicrobesonrheumaticdiseasesabibliometricanalysis
AT lujianyu effectsofintestinalmicrobesonrheumaticdiseasesabibliometricanalysis
AT zhangwei effectsofintestinalmicrobesonrheumaticdiseasesabibliometricanalysis
AT qianweijin effectsofintestinalmicrobesonrheumaticdiseasesabibliometricanalysis
AT tangjieling effectsofintestinalmicrobesonrheumaticdiseasesabibliometricanalysis
AT yangyiting effectsofintestinalmicrobesonrheumaticdiseasesabibliometricanalysis
AT lubingnan effectsofintestinalmicrobesonrheumaticdiseasesabibliometricanalysis
AT changzhengyan effectsofintestinalmicrobesonrheumaticdiseasesabibliometricanalysis
AT liuxin effectsofintestinalmicrobesonrheumaticdiseasesabibliometricanalysis
AT jishizhao effectsofintestinalmicrobesonrheumaticdiseasesabibliometricanalysis