PERK/ATF4-dependent expression of the stress response protein REDD1 promotes proinflammatory cytokine expression in the heart of obese mice

Endoplasmic reticulum (ER) stress and inflammation are hallmarks of myocardial impairment. Here, we investigated the role of the stress response protein regulated in development and DNA damage 1 (REDD1) as a molecular link between ER stress and inflammation in cardiomyocytes. In mice fed a high-fat...

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Detalles Bibliográficos
Autores principales: Stevens, Shaunaci A., Gonzalez Aguiar, Maria K., Toro, Allyson L., Yerlikaya, Esma I., Sunilkumar, Siddharth, VanCleave, Ashley M., Pfleger, Jessica, Bradley, Elisa A., Kimball, Scot R., Dennis, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870577/
https://www.ncbi.nlm.nih.gov/pubmed/36383638
http://dx.doi.org/10.1152/ajpendo.00238.2022

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