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Clinical Evaluation of IDH Mutation Status in Formalin-Fixed Paraffin-Embedded Tissue in Gliomas

BACKGROUND AND OBJECTIVE: Determination of isocitrate dehydrogenase (IDH) 1/2 mutational status is crucial for a glioma diagnosis. It is common for IDH mutational status to be determined via a two-step algorithm that utilizes immunohistochemistry studies for IDH1 R132H, the most frequent variant, fo...

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Detalles Bibliográficos
Autores principales:	Nelson, Ernest J., Gubbiotti, Maria A., Carlin, Alicia M., Nasrallah, MacLean P., Van Deerlin, Vivianna M., Herlihy, Sarah E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2023
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870658/ https://www.ncbi.nlm.nih.gov/pubmed/36690887 http://dx.doi.org/10.1007/s40291-022-00638-7

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