TRIM24 controls induction of latent HIV-1 by stimulating transcriptional elongation

Binding of USF1/2 and TFII-I (RBF-2) at conserved sites flanking the HIV-1 LTR enhancer is essential for reactivation from latency in T cells, with TFII-I knockdown rendering the provirus insensitive to T cell signaling. We identified an interaction of TFII-I with the tripartite motif protein TRIM24...

Descripción completa

Detalles Bibliográficos
Autores principales: Horvath, Riley M., Dahabieh, Matthew, Malcolm, Tom, Sadowski, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870992/
https://www.ncbi.nlm.nih.gov/pubmed/36690785
http://dx.doi.org/10.1038/s42003-023-04484-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870992/
https://www.ncbi.nlm.nih.gov/pubmed/36690785
http://dx.doi.org/10.1038/s42003-023-04484-z

Ejemplares similares