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TRIM24 controls induction of latent HIV-1 by stimulating transcriptional elongation

Binding of USF1/2 and TFII-I (RBF-2) at conserved sites flanking the HIV-1 LTR enhancer is essential for reactivation from latency in T cells, with TFII-I knockdown rendering the provirus insensitive to T cell signaling. We identified an interaction of TFII-I with the tripartite motif protein TRIM24...

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Detalles Bibliográficos
Autores principales:	Horvath, Riley M., Dahabieh, Matthew, Malcolm, Tom, Sadowski, Ivan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9870992/ https://www.ncbi.nlm.nih.gov/pubmed/36690785 http://dx.doi.org/10.1038/s42003-023-04484-z

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