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Discovery of structural and functional transition sites for membrane-penetrating activity of sheep myeloid antimicrobial peptide-18
Cathelicidin antimicrobial peptides have an extended and/or unstructured conformation in aqueous solutions but fold into ordered conformations, such as the α-helical structure, when interacting with cellular membranes. These structural transitions can be directly correlated to their antimicrobial ac...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871035/ https://www.ncbi.nlm.nih.gov/pubmed/36690720 http://dx.doi.org/10.1038/s41598-023-28386-6 |