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Protocols for single-cell RNA-seq and spatial gene expression integration and interactive visualization

There is a wealth of software that utilizes single-cell RNA-seq (scRNA-seq) data to deconvolve spatial transcriptomic spots, which currently are not yet at single-cell resolution. Here we provide protocols for implementing Seurat and Giotto packages to elucidate cell-type distribution in our example...

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Detalles Bibliográficos
Autores principales: Sona, Surbhi, Bradley, Matthew, Ting, Angela H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871342/
https://www.ncbi.nlm.nih.gov/pubmed/36853708
http://dx.doi.org/10.1016/j.xpro.2023.102047

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