Cargando…

Data-driven approach to integrating genomic and behavioral preclinical traumatic brain injury research

Understanding recovery from TBI is complex, involving multiple systems and modalities. The current study applied modern data science tools to manage this complexity and harmonize large-scale data to understand relationships between gene expression and behavioral outcomes in a preclinical model of ch...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huie, J. Russell, Nielson, Jessica L., Wolfsbane, Jorden, Andersen, Clark R., Spratt, Heidi M., DeWitt, Douglas S., Ferguson, Adam R., Hawkins, Bridget E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871446/ https://www.ncbi.nlm.nih.gov/pubmed/36704298 http://dx.doi.org/10.3389/fbioe.2022.887898

Ejemplares similares

Pleiotropic Effects of Simvastatin and Losartan in Preclinical Models of Post-Traumatic Elbow Contracture
por: David, Michael A., et al.
Publicado: (2022)

The three-dimension preclinical models for ferroptosis monitoring
por: Meng, Yiming, et al.
Publicado: (2022)

Preclinical Validation of SilkBridge(TM) for Peripheral Nerve Regeneration
por: Fregnan, Federica, et al.
Publicado: (2020)

Recent advances in the repair of degenerative intervertebral disc for preclinical applications
por: Ying, Yijian, et al.
Publicado: (2023)

The efficacy of femoral augmentation for hip fracture prevention using ceramic-based cements: A preliminary experimentally-driven finite element investigation
por: Fung, Anita, et al.
Publicado: (2023)

Preclinical ex-vivo Testing of Anti-inflammatory Drugs in a Bovine Intervertebral Degenerative Disc Model
por: Li, Zhen, et al.
Publicado: (2020)

Nanomaterial Nitric Oxide Delivery in Traumatic Orthopedic Regenerative Medicine
por: Anastasio, Albert Thomas, et al.
Publicado: (2021)

The Injury Mechanism of Traumatic Amputation
por: Rankin, Iain A., et al.
Publicado: (2021)

An Effective Translation: The Development of Hyaluronan-Based Medical Products From the Physicochemical, and Preclinical Aspects
por: Huerta-Ángeles, Gloria, et al.
Publicado: (2018)

Development of Subject Specific Finite Element Models of the Mouse Knee Joint for Preclinical Applications
por: Zanjani-Pour, Sahand, et al.
Publicado: (2020)

Comprehensive Review on Current and Future Regulatory Requirements on Wearable Sensors in Preclinical and Clinical Testing
por: Ravizza, Alice, et al.
Publicado: (2019)

Systematic Review of the Preclinical Technology Readiness of Orthopedic Gene Therapy and Outlook for Clinical Translation
por: Wilkinson, Piers, et al.
Publicado: (2021)

Preclinical in vitro evaluation of implantable materials: conventional approaches, new models and future directions
por: Frisch, Emilie, et al.
Publicado: (2023)

Omics-Driven Biotechnology for Industrial Applications
por: Amer, Bashar, et al.
Publicado: (2021)

Biomechanical Assessment of the Validity of Sheep as a Preclinical Model for Testing Mandibular Fracture Fixation Devices
por: Orassi, Vincenzo, et al.
Publicado: (2021)

Brain architecture-based vulnerability to traumatic injury
por: Rifkin, Jared A., et al.
Publicado: (2022)

3D Printing of Bone Grafts for Cleft Alveolar Osteoplasty – In vivo Evaluation in a Preclinical Model
por: Korn, Paula, et al.
Publicado: (2020)

SMaRT modulation of tau isoforms rescues cognitive and motor impairments in a preclinical model of tauopathy
por: Muñiz, Javier Andrés, et al.
Publicado: (2022)

Comprehensive ex vivo and in vivo preclinical evaluation of novel chemo enzymatic decellularized peripheral nerve allografts
por: García-García, Óscar Darío, et al.
Publicado: (2023)

Role of BMP-7 on biological parameters osseointegration of dental implants: Preliminary results of a preclinical study
por: López-Valverde, Nansi, et al.
Publicado: (2023)

Insights and future directions for the application of perinatal derivatives in eye diseases: A critical review of preclinical and clinical studies
por: Norte-Muñoz, María, et al.
Publicado: (2022)

Macrophage-Driven Biomaterial Degradation Depends on Scaffold Microarchitecture
por: Wissing, Tamar B., et al.
Publicado: (2019)

Specification-driven acceptance criteria for validation of biopharmaceutical processes
por: Marschall, Lukas, et al.
Publicado: (2022)

Bio-driven visual saliency detection with color factor
por: Wang, Yan, et al.
Publicado: (2022)

Editorial: Post-Traumatic Osteoarthritis After Meniscus Injury
por: Patel, Jay M., et al.
Publicado: (2022)

Sensor-Based Nerve Compression Measurement: A Scoping Review of Current Concepts and a Preclinical Evaluation of Commercial Microsensors
por: Daeschler, Simeon C., et al.
Publicado: (2022)

Recent Advances of Pullulan and/or Dextran-Based Materials for Bone Tissue Engineering Strategies in Preclinical Studies: A Systematic Review
por: Ahmed Omar, Naïma, et al.
Publicado: (2022)

A Morphological Study of the Meniscus, Cartilage and Subchondral Bone Following Closed-Joint Traumatic Impact to the Knee
por: Haut Donahue, T. L., et al.
Publicado: (2022)

Voluntary-Driven Elbow Orthosis with Speed-Controlled Tremor Suppression
por: Herrnstadt, Gil, et al.
Publicado: (2016)

Haptic Glove Using Tendon-Driven Soft Robotic Mechanism
por: Baik, Siyeon, et al.
Publicado: (2020)

Synthetic Biology-Driven Microbial Production of Resveratrol: Advances and Perspectives
por: Feng, Chao, et al.
Publicado: (2022)

Systems and synthetic biology-driven engineering of live bacterial therapeutics
por: Kim, Kangsan, et al.
Publicado: (2023)

A human surrogate neck for traumatic brain injury research
por: Farmer, Jon, et al.
Publicado: (2022)

A Self-Setting Hydrogel of Silylated Chitosan and Cellulose for the Repair of Osteochondral Defects: From in vitro Characterization to Preclinical Evaluation in Dogs
por: Boyer, Cécile, et al.
Publicado: (2020)

Vascular Calcification: Is it rather a Stem/Progenitor Cells Driven Phenomenon?
por: Leszczynska, Aleksandra, et al.
Publicado: (2018)

Soft Pneumatic Gripper With a Tendon-Driven Soft Origami Pump
por: Kim, Yeunhee, et al.
Publicado: (2020)

Corrigendum: Haptic Glove Using Tendon-Driven Soft Robotic Mechanism
por: Baik, Siyeon, et al.
Publicado: (2020)

Shear-driven modelling of thrombus formation in type B aortic dissection
por: Jafarinia, Alireza, et al.
Publicado: (2022)

System dynamics modeling for traumatic brain injury: Mini-review of applications
por: Kenzie, Erin S., et al.
Publicado: (2022)

Low-Rank Representation of Head Impact Kinematics: A Data-Driven Emulator
por: Arrué, Patricio, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_r5cumouqt4177a8gf7qna23cva