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A role of salt bridges in mediating drug potency: A lesson from the N-myristoyltransferase inhibitors
The salt bridge is the strongest non-covalent interaction in nature and is known to participate in protein folding, protein-protein interactions, and molecular recognition. However, the role of salt bridges in the context of drug design has remained not well understood. Here, we report that a common...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871453/ https://www.ncbi.nlm.nih.gov/pubmed/36703920 http://dx.doi.org/10.3389/fmolb.2022.1066029 |