Cargando…
The role of the endolysosomal pathway in α-synuclein pathogenesis in Parkinson’s disease
Parkinson’s disease (PD) is a chronic neurodegenerative disease that is characterized by a loss of dopaminergic neurons in the substantia nigra pars compacta of the midbrain (SNpc). Extensive studies into genetic and cellular models of PD implicate protein trafficking as a prominent contributor to t...
Autores principales: | Smith, Jessica K., Mellick, George D., Sykes, Alex M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871505/ https://www.ncbi.nlm.nih.gov/pubmed/36704248 http://dx.doi.org/10.3389/fncel.2022.1081426 |
Ejemplares similares
-
Nanoparticles With Affinity for α-Synuclein Sequester α-Synuclein to Form Toxic Aggregates in Neurons With Endolysosomal Impairment
por: Jiang, Peizhou, et al.
Publicado: (2021) -
The Roles of Post-translational Modifications on α-Synuclein in the Pathogenesis of Parkinson’s Diseases
por: Zhang, Jiaming, et al.
Publicado: (2019) -
Proteostasis of α-Synuclein and Its Role in the Pathogenesis of Parkinson’s Disease
por: Han, Deqiang, et al.
Publicado: (2020) -
α-synuclein pathogenesis in hiPSC models of Parkinson’s disease
por: Baena-Montes, Jara M., et al.
Publicado: (2021) -
Lipids as Trans-Acting Effectors for α-Synuclein in the Pathogenesis of Parkinson’s Disease
por: Ikenaka, Kensuke, et al.
Publicado: (2019)