Involvement of SUR2/Kir6.1 channel in the physiopathology of pulmonary arterial hypertension

AIMS: We hypothesized that the ATP-sensitive K(+) channels (KATP) regulatory subunit (ABCC9) contributes to PAH pathogenesis. ABCC9 gene encodes for two regulatory subunits of KATP channels: the SUR2A and SUR2B proteins. In the KATP channel, the SUR2 subunits are associated with the K(+) channel Kir...

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Detalles Bibliográficos
Autores principales: Le Ribeuz, Hélène, Masson, Bastien, Dutheil, Mary, Boët, Angèle, Beauvais, Antoine, Sabourin, Jessica, De Montpreville, Vincent Thomas, Capuano, Véronique, Mercier, Olaf, Humbert, Marc, Montani, David, Antigny, Fabrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871631/
https://www.ncbi.nlm.nih.gov/pubmed/36704469
http://dx.doi.org/10.3389/fcvm.2022.1066047

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