GAT inhibition preserves cerebral blood flow and reduces oxidant damage to mitochondria in rodents exposed to extreme hyperbaric oxygen

Oxygen breathing at elevated partial pressures (PO(2)’s) at or more than 3 atmospheres absolute (ATA) causes a reduction in brain γ-aminobutyric acid (GABA) levels that impacts the development of central nervous system oxygen toxicity (CNS-OT). Drugs that increase brain GABA content delay the onset...

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Detalles Bibliográficos
Autores principales: Demchenko, Ivan T., Suliman, Hagir B., Zhilyaey, Sergey Y., Alekseeva, Olga S., Platonova, Tatyana F., Makowski, Matthew S., Piantadosi, Claude A., Gasier, Heath G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871636/
https://www.ncbi.nlm.nih.gov/pubmed/36704328
http://dx.doi.org/10.3389/fnmol.2022.1062410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871636/
https://www.ncbi.nlm.nih.gov/pubmed/36704328
http://dx.doi.org/10.3389/fnmol.2022.1062410

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