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Leukemia-associated truncation of granulocyte colony-stimulating factor receptor impacts granulopoiesis throughout the life-course

INTRODUCTION: The granulocyte colony-stimulating factor receptor (G-CSFR), encoded by the CSF3R gene, is involved in the production and function of neutrophilic granulocytes. Somatic mutations in CSF3R leading to truncated G-CSFR forms are observed in acute myeloid leukemia (AML), particularly those...

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Detalles Bibliográficos
Autores principales:	Bulleeraz, Vilasha, Goy, Michelle, Basheer, Faiza, Liongue, Clifford, Ward, Alister C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871641/ https://www.ncbi.nlm.nih.gov/pubmed/36703974 http://dx.doi.org/10.3389/fimmu.2022.1095453

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