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Homoarginine and creatine deficiency do not exacerbate murine ischaemic heart failure

AIMS: Low levels of homoarginine and creatine are associated with heart failure severity in humans, but it is unclear to what extent they contribute to pathophysiology. Both are synthesized via L‐arginine:glycine amidinotransferase (AGAT), such that AGAT(−/−) mice have a combined creatine and homoar...

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Detalles Bibliográficos
Autores principales:	McAndrew, Debra J., Lake, Hannah A., Zervou, Sevasti, Schwedhelm, Edzard, Schneider, Jurgen E., Neubauer, Stefan, Lygate, Craig A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871656/ https://www.ncbi.nlm.nih.gov/pubmed/36178450 http://dx.doi.org/10.1002/ehf2.14183

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