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What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare multisystem disorder; cardiac involvement may include eosinophilic myocarditis. A 67‐year‐old woman presented with 1‐week history of dyspnoea and orthopnoea. She had a history of adult‐onset asthma and peripheral eosinophilia. The invest...

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Autores principales: Amelotti, Nicola, Mapelli, Massimo, Guglielmo, Marco, Pires, Maria Inês Fiuza Branco, Campodonico, Jeness, Majocchi, Benedetta, Ribatti, Valentina, Vettor, Giulia, Baggiano, Andrea, Catto, Valentina, Basso, Cristina, Pontone, Gianluca, Agostoni, Piergiuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871676/
https://www.ncbi.nlm.nih.gov/pubmed/36259268
http://dx.doi.org/10.1002/ehf2.14172
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author Amelotti, Nicola
Mapelli, Massimo
Guglielmo, Marco
Pires, Maria Inês Fiuza Branco
Campodonico, Jeness
Majocchi, Benedetta
Ribatti, Valentina
Vettor, Giulia
Baggiano, Andrea
Catto, Valentina
Basso, Cristina
Pontone, Gianluca
Agostoni, Piergiuseppe
author_facet Amelotti, Nicola
Mapelli, Massimo
Guglielmo, Marco
Pires, Maria Inês Fiuza Branco
Campodonico, Jeness
Majocchi, Benedetta
Ribatti, Valentina
Vettor, Giulia
Baggiano, Andrea
Catto, Valentina
Basso, Cristina
Pontone, Gianluca
Agostoni, Piergiuseppe
author_sort Amelotti, Nicola
collection PubMed
description Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare multisystem disorder; cardiac involvement may include eosinophilic myocarditis. A 67‐year‐old woman presented with 1‐week history of dyspnoea and orthopnoea. She had a history of adult‐onset asthma and peripheral eosinophilia. The investigations showed T‐wave inversion on lateral leads, peripheral eosinophilia, elevated troponin and BNP values, and severe biventricular systolic dysfunction with diffuse hypokinesia and apical akinesia. Computed tomography excluded coronary disease and showed bilateral basal ground‐glass opacities, air‐space consolidation, and bilateral reticular‐nodular pattern. Cardiac magnetic resonance findings were compatible with active myocardial inflammation. An endomyocardial biopsy (EMB) confirmed the diagnosis of eosinophilic myocarditis, and a therapy with oral corticosteroids and heart failure medications was started.
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spelling pubmed-98716762023-01-25 What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure Amelotti, Nicola Mapelli, Massimo Guglielmo, Marco Pires, Maria Inês Fiuza Branco Campodonico, Jeness Majocchi, Benedetta Ribatti, Valentina Vettor, Giulia Baggiano, Andrea Catto, Valentina Basso, Cristina Pontone, Gianluca Agostoni, Piergiuseppe ESC Heart Fail Case Reports Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare multisystem disorder; cardiac involvement may include eosinophilic myocarditis. A 67‐year‐old woman presented with 1‐week history of dyspnoea and orthopnoea. She had a history of adult‐onset asthma and peripheral eosinophilia. The investigations showed T‐wave inversion on lateral leads, peripheral eosinophilia, elevated troponin and BNP values, and severe biventricular systolic dysfunction with diffuse hypokinesia and apical akinesia. Computed tomography excluded coronary disease and showed bilateral basal ground‐glass opacities, air‐space consolidation, and bilateral reticular‐nodular pattern. Cardiac magnetic resonance findings were compatible with active myocardial inflammation. An endomyocardial biopsy (EMB) confirmed the diagnosis of eosinophilic myocarditis, and a therapy with oral corticosteroids and heart failure medications was started. John Wiley and Sons Inc. 2022-10-19 /pmc/articles/PMC9871676/ /pubmed/36259268 http://dx.doi.org/10.1002/ehf2.14172 Text en © 2022 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Amelotti, Nicola
Mapelli, Massimo
Guglielmo, Marco
Pires, Maria Inês Fiuza Branco
Campodonico, Jeness
Majocchi, Benedetta
Ribatti, Valentina
Vettor, Giulia
Baggiano, Andrea
Catto, Valentina
Basso, Cristina
Pontone, Gianluca
Agostoni, Piergiuseppe
What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure
title What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure
title_full What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure
title_fullStr What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure
title_full_unstemmed What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure
title_short What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure
title_sort what's behind your eosinophilic myocarditis? a case of churg–strauss syndrome diagnosed during acute heart failure
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871676/
https://www.ncbi.nlm.nih.gov/pubmed/36259268
http://dx.doi.org/10.1002/ehf2.14172
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