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What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare multisystem disorder; cardiac involvement may include eosinophilic myocarditis. A 67‐year‐old woman presented with 1‐week history of dyspnoea and orthopnoea. She had a history of adult‐onset asthma and peripheral eosinophilia. The invest...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871676/ https://www.ncbi.nlm.nih.gov/pubmed/36259268 http://dx.doi.org/10.1002/ehf2.14172 |
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author | Amelotti, Nicola Mapelli, Massimo Guglielmo, Marco Pires, Maria Inês Fiuza Branco Campodonico, Jeness Majocchi, Benedetta Ribatti, Valentina Vettor, Giulia Baggiano, Andrea Catto, Valentina Basso, Cristina Pontone, Gianluca Agostoni, Piergiuseppe |
author_facet | Amelotti, Nicola Mapelli, Massimo Guglielmo, Marco Pires, Maria Inês Fiuza Branco Campodonico, Jeness Majocchi, Benedetta Ribatti, Valentina Vettor, Giulia Baggiano, Andrea Catto, Valentina Basso, Cristina Pontone, Gianluca Agostoni, Piergiuseppe |
author_sort | Amelotti, Nicola |
collection | PubMed |
description | Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare multisystem disorder; cardiac involvement may include eosinophilic myocarditis. A 67‐year‐old woman presented with 1‐week history of dyspnoea and orthopnoea. She had a history of adult‐onset asthma and peripheral eosinophilia. The investigations showed T‐wave inversion on lateral leads, peripheral eosinophilia, elevated troponin and BNP values, and severe biventricular systolic dysfunction with diffuse hypokinesia and apical akinesia. Computed tomography excluded coronary disease and showed bilateral basal ground‐glass opacities, air‐space consolidation, and bilateral reticular‐nodular pattern. Cardiac magnetic resonance findings were compatible with active myocardial inflammation. An endomyocardial biopsy (EMB) confirmed the diagnosis of eosinophilic myocarditis, and a therapy with oral corticosteroids and heart failure medications was started. |
format | Online Article Text |
id | pubmed-9871676 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-98716762023-01-25 What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure Amelotti, Nicola Mapelli, Massimo Guglielmo, Marco Pires, Maria Inês Fiuza Branco Campodonico, Jeness Majocchi, Benedetta Ribatti, Valentina Vettor, Giulia Baggiano, Andrea Catto, Valentina Basso, Cristina Pontone, Gianluca Agostoni, Piergiuseppe ESC Heart Fail Case Reports Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare multisystem disorder; cardiac involvement may include eosinophilic myocarditis. A 67‐year‐old woman presented with 1‐week history of dyspnoea and orthopnoea. She had a history of adult‐onset asthma and peripheral eosinophilia. The investigations showed T‐wave inversion on lateral leads, peripheral eosinophilia, elevated troponin and BNP values, and severe biventricular systolic dysfunction with diffuse hypokinesia and apical akinesia. Computed tomography excluded coronary disease and showed bilateral basal ground‐glass opacities, air‐space consolidation, and bilateral reticular‐nodular pattern. Cardiac magnetic resonance findings were compatible with active myocardial inflammation. An endomyocardial biopsy (EMB) confirmed the diagnosis of eosinophilic myocarditis, and a therapy with oral corticosteroids and heart failure medications was started. John Wiley and Sons Inc. 2022-10-19 /pmc/articles/PMC9871676/ /pubmed/36259268 http://dx.doi.org/10.1002/ehf2.14172 Text en © 2022 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Case Reports Amelotti, Nicola Mapelli, Massimo Guglielmo, Marco Pires, Maria Inês Fiuza Branco Campodonico, Jeness Majocchi, Benedetta Ribatti, Valentina Vettor, Giulia Baggiano, Andrea Catto, Valentina Basso, Cristina Pontone, Gianluca Agostoni, Piergiuseppe What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure |
title | What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure |
title_full | What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure |
title_fullStr | What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure |
title_full_unstemmed | What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure |
title_short | What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure |
title_sort | what's behind your eosinophilic myocarditis? a case of churg–strauss syndrome diagnosed during acute heart failure |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871676/ https://www.ncbi.nlm.nih.gov/pubmed/36259268 http://dx.doi.org/10.1002/ehf2.14172 |
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