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Characteristics and management of very elderly patients with heart failure: a retrospective, population cohort study

AIMS: Unmet needs exist in the diagnosis and treatment of heart failure (HF) in the elderly population. Our aim was to analyse and compare data of diagnostics and management of very elderly patients (aged ≥85 years) compared with younger patients (aged 18–84 years) with HF in Sweden. METHODS: Incide...

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Autores principales: Olofsson, Mona, Lindmark, Krister, Stålhammar, Jan, Törnblom, Michael, Lundberg, Anna, Wikström, Gerhard, Boman, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871701/
https://www.ncbi.nlm.nih.gov/pubmed/36208123
http://dx.doi.org/10.1002/ehf2.14191
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author Olofsson, Mona
Lindmark, Krister
Stålhammar, Jan
Törnblom, Michael
Lundberg, Anna
Wikström, Gerhard
Boman, Kurt
author_facet Olofsson, Mona
Lindmark, Krister
Stålhammar, Jan
Törnblom, Michael
Lundberg, Anna
Wikström, Gerhard
Boman, Kurt
author_sort Olofsson, Mona
collection PubMed
description AIMS: Unmet needs exist in the diagnosis and treatment of heart failure (HF) in the elderly population. Our aim was to analyse and compare data of diagnostics and management of very elderly patients (aged ≥85 years) compared with younger patients (aged 18–84 years) with HF in Sweden. METHODS: Incidence of ≥2 HF diagnosis (ICD‐10) was identified from primary/secondary care in Uppsala and Västerbotten during 2010–2015 via electronic medical records linked to data from national health registers. Analyses investigated the diagnosis, treatment patterns, hospitalizations and outpatient visits, and mortality. RESULTS: Of 8702 patients, 27.7% were ≥85 years old, women (60.2%); most patients (80.7%) had unknown left ventricular ejection fraction; key co‐morbidities comprised anaemia, dementia, and cerebrovascular disease. More very elderly patients received cardiovascular disease (CVD)‐related management after diagnosis in primary care (13.6% vs. 6.5%; P < 0.0001), but fewer patients underwent echocardiography (19.3% vs. 42.9%; P < 0.0001). Within 1 year of diagnosis, very elderly patients were less likely to be hospitalized (all‐cause admissions per patient: 1.9 vs. 2.3; P < 0.0001; CVD‐related admissions per patient: 1.8 vs. 2.1; P = 0.0004) or prescribed an angiotensin‐converting enzyme inhibitor/angiotensin receptor blocker (ACEI/ARB) plus a β‐blocker (45.2% vs. 56.9%; P < 0.0001) or an ACEI/ARB plus a β‐blocker plus a mineralocorticoid receptor antagonist (15.4% vs. 31.7%; P < 0.0001). One‐year mortality was high in patients ≥85 years old, 30.5% (CI: 28.3‐32.7%) out of 1797 patients. CONCLUSIONS: Despite the large number of very elderly patients with newly diagnosed HF in Sweden, poor diagnostic work‐up and subsequent treatment highlight the inequality of care in this vulnerable population.
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spelling pubmed-98717012023-01-25 Characteristics and management of very elderly patients with heart failure: a retrospective, population cohort study Olofsson, Mona Lindmark, Krister Stålhammar, Jan Törnblom, Michael Lundberg, Anna Wikström, Gerhard Boman, Kurt ESC Heart Fail Original Articles AIMS: Unmet needs exist in the diagnosis and treatment of heart failure (HF) in the elderly population. Our aim was to analyse and compare data of diagnostics and management of very elderly patients (aged ≥85 years) compared with younger patients (aged 18–84 years) with HF in Sweden. METHODS: Incidence of ≥2 HF diagnosis (ICD‐10) was identified from primary/secondary care in Uppsala and Västerbotten during 2010–2015 via electronic medical records linked to data from national health registers. Analyses investigated the diagnosis, treatment patterns, hospitalizations and outpatient visits, and mortality. RESULTS: Of 8702 patients, 27.7% were ≥85 years old, women (60.2%); most patients (80.7%) had unknown left ventricular ejection fraction; key co‐morbidities comprised anaemia, dementia, and cerebrovascular disease. More very elderly patients received cardiovascular disease (CVD)‐related management after diagnosis in primary care (13.6% vs. 6.5%; P < 0.0001), but fewer patients underwent echocardiography (19.3% vs. 42.9%; P < 0.0001). Within 1 year of diagnosis, very elderly patients were less likely to be hospitalized (all‐cause admissions per patient: 1.9 vs. 2.3; P < 0.0001; CVD‐related admissions per patient: 1.8 vs. 2.1; P = 0.0004) or prescribed an angiotensin‐converting enzyme inhibitor/angiotensin receptor blocker (ACEI/ARB) plus a β‐blocker (45.2% vs. 56.9%; P < 0.0001) or an ACEI/ARB plus a β‐blocker plus a mineralocorticoid receptor antagonist (15.4% vs. 31.7%; P < 0.0001). One‐year mortality was high in patients ≥85 years old, 30.5% (CI: 28.3‐32.7%) out of 1797 patients. CONCLUSIONS: Despite the large number of very elderly patients with newly diagnosed HF in Sweden, poor diagnostic work‐up and subsequent treatment highlight the inequality of care in this vulnerable population. John Wiley and Sons Inc. 2022-10-08 /pmc/articles/PMC9871701/ /pubmed/36208123 http://dx.doi.org/10.1002/ehf2.14191 Text en © 2022 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Olofsson, Mona
Lindmark, Krister
Stålhammar, Jan
Törnblom, Michael
Lundberg, Anna
Wikström, Gerhard
Boman, Kurt
Characteristics and management of very elderly patients with heart failure: a retrospective, population cohort study
title Characteristics and management of very elderly patients with heart failure: a retrospective, population cohort study
title_full Characteristics and management of very elderly patients with heart failure: a retrospective, population cohort study
title_fullStr Characteristics and management of very elderly patients with heart failure: a retrospective, population cohort study
title_full_unstemmed Characteristics and management of very elderly patients with heart failure: a retrospective, population cohort study
title_short Characteristics and management of very elderly patients with heart failure: a retrospective, population cohort study
title_sort characteristics and management of very elderly patients with heart failure: a retrospective, population cohort study
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871701/
https://www.ncbi.nlm.nih.gov/pubmed/36208123
http://dx.doi.org/10.1002/ehf2.14191
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