Cargando…
Characteristics and management of very elderly patients with heart failure: a retrospective, population cohort study
AIMS: Unmet needs exist in the diagnosis and treatment of heart failure (HF) in the elderly population. Our aim was to analyse and compare data of diagnostics and management of very elderly patients (aged ≥85 years) compared with younger patients (aged 18–84 years) with HF in Sweden. METHODS: Incide...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871701/ https://www.ncbi.nlm.nih.gov/pubmed/36208123 http://dx.doi.org/10.1002/ehf2.14191 |
_version_ | 1784877237529477120 |
---|---|
author | Olofsson, Mona Lindmark, Krister Stålhammar, Jan Törnblom, Michael Lundberg, Anna Wikström, Gerhard Boman, Kurt |
author_facet | Olofsson, Mona Lindmark, Krister Stålhammar, Jan Törnblom, Michael Lundberg, Anna Wikström, Gerhard Boman, Kurt |
author_sort | Olofsson, Mona |
collection | PubMed |
description | AIMS: Unmet needs exist in the diagnosis and treatment of heart failure (HF) in the elderly population. Our aim was to analyse and compare data of diagnostics and management of very elderly patients (aged ≥85 years) compared with younger patients (aged 18–84 years) with HF in Sweden. METHODS: Incidence of ≥2 HF diagnosis (ICD‐10) was identified from primary/secondary care in Uppsala and Västerbotten during 2010–2015 via electronic medical records linked to data from national health registers. Analyses investigated the diagnosis, treatment patterns, hospitalizations and outpatient visits, and mortality. RESULTS: Of 8702 patients, 27.7% were ≥85 years old, women (60.2%); most patients (80.7%) had unknown left ventricular ejection fraction; key co‐morbidities comprised anaemia, dementia, and cerebrovascular disease. More very elderly patients received cardiovascular disease (CVD)‐related management after diagnosis in primary care (13.6% vs. 6.5%; P < 0.0001), but fewer patients underwent echocardiography (19.3% vs. 42.9%; P < 0.0001). Within 1 year of diagnosis, very elderly patients were less likely to be hospitalized (all‐cause admissions per patient: 1.9 vs. 2.3; P < 0.0001; CVD‐related admissions per patient: 1.8 vs. 2.1; P = 0.0004) or prescribed an angiotensin‐converting enzyme inhibitor/angiotensin receptor blocker (ACEI/ARB) plus a β‐blocker (45.2% vs. 56.9%; P < 0.0001) or an ACEI/ARB plus a β‐blocker plus a mineralocorticoid receptor antagonist (15.4% vs. 31.7%; P < 0.0001). One‐year mortality was high in patients ≥85 years old, 30.5% (CI: 28.3‐32.7%) out of 1797 patients. CONCLUSIONS: Despite the large number of very elderly patients with newly diagnosed HF in Sweden, poor diagnostic work‐up and subsequent treatment highlight the inequality of care in this vulnerable population. |
format | Online Article Text |
id | pubmed-9871701 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-98717012023-01-25 Characteristics and management of very elderly patients with heart failure: a retrospective, population cohort study Olofsson, Mona Lindmark, Krister Stålhammar, Jan Törnblom, Michael Lundberg, Anna Wikström, Gerhard Boman, Kurt ESC Heart Fail Original Articles AIMS: Unmet needs exist in the diagnosis and treatment of heart failure (HF) in the elderly population. Our aim was to analyse and compare data of diagnostics and management of very elderly patients (aged ≥85 years) compared with younger patients (aged 18–84 years) with HF in Sweden. METHODS: Incidence of ≥2 HF diagnosis (ICD‐10) was identified from primary/secondary care in Uppsala and Västerbotten during 2010–2015 via electronic medical records linked to data from national health registers. Analyses investigated the diagnosis, treatment patterns, hospitalizations and outpatient visits, and mortality. RESULTS: Of 8702 patients, 27.7% were ≥85 years old, women (60.2%); most patients (80.7%) had unknown left ventricular ejection fraction; key co‐morbidities comprised anaemia, dementia, and cerebrovascular disease. More very elderly patients received cardiovascular disease (CVD)‐related management after diagnosis in primary care (13.6% vs. 6.5%; P < 0.0001), but fewer patients underwent echocardiography (19.3% vs. 42.9%; P < 0.0001). Within 1 year of diagnosis, very elderly patients were less likely to be hospitalized (all‐cause admissions per patient: 1.9 vs. 2.3; P < 0.0001; CVD‐related admissions per patient: 1.8 vs. 2.1; P = 0.0004) or prescribed an angiotensin‐converting enzyme inhibitor/angiotensin receptor blocker (ACEI/ARB) plus a β‐blocker (45.2% vs. 56.9%; P < 0.0001) or an ACEI/ARB plus a β‐blocker plus a mineralocorticoid receptor antagonist (15.4% vs. 31.7%; P < 0.0001). One‐year mortality was high in patients ≥85 years old, 30.5% (CI: 28.3‐32.7%) out of 1797 patients. CONCLUSIONS: Despite the large number of very elderly patients with newly diagnosed HF in Sweden, poor diagnostic work‐up and subsequent treatment highlight the inequality of care in this vulnerable population. John Wiley and Sons Inc. 2022-10-08 /pmc/articles/PMC9871701/ /pubmed/36208123 http://dx.doi.org/10.1002/ehf2.14191 Text en © 2022 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Original Articles Olofsson, Mona Lindmark, Krister Stålhammar, Jan Törnblom, Michael Lundberg, Anna Wikström, Gerhard Boman, Kurt Characteristics and management of very elderly patients with heart failure: a retrospective, population cohort study |
title | Characteristics and management of very elderly patients with heart failure: a retrospective, population cohort study |
title_full | Characteristics and management of very elderly patients with heart failure: a retrospective, population cohort study |
title_fullStr | Characteristics and management of very elderly patients with heart failure: a retrospective, population cohort study |
title_full_unstemmed | Characteristics and management of very elderly patients with heart failure: a retrospective, population cohort study |
title_short | Characteristics and management of very elderly patients with heart failure: a retrospective, population cohort study |
title_sort | characteristics and management of very elderly patients with heart failure: a retrospective, population cohort study |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871701/ https://www.ncbi.nlm.nih.gov/pubmed/36208123 http://dx.doi.org/10.1002/ehf2.14191 |
work_keys_str_mv | AT olofssonmona characteristicsandmanagementofveryelderlypatientswithheartfailurearetrospectivepopulationcohortstudy AT lindmarkkrister characteristicsandmanagementofveryelderlypatientswithheartfailurearetrospectivepopulationcohortstudy AT stalhammarjan characteristicsandmanagementofveryelderlypatientswithheartfailurearetrospectivepopulationcohortstudy AT tornblommichael characteristicsandmanagementofveryelderlypatientswithheartfailurearetrospectivepopulationcohortstudy AT lundberganna characteristicsandmanagementofveryelderlypatientswithheartfailurearetrospectivepopulationcohortstudy AT wikstromgerhard characteristicsandmanagementofveryelderlypatientswithheartfailurearetrospectivepopulationcohortstudy AT bomankurt characteristicsandmanagementofveryelderlypatientswithheartfailurearetrospectivepopulationcohortstudy |