Direct actions of dapagliflozin and interactions with LCZ696 and spironolactone on cardiac fibroblasts of patients with heart failure and reduced ejection fraction

AIMS: Inhibitors of SGLT2 (SGLT2i) have shown a positive impact in patients with chronic heart failure and reduced ejection fraction (HFrEF). Nonetheless, the direct effects of SGLT2i on cardiac cells and how their association with main drugs used for HFrEF affect the behaviour and signalling pathwa...

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Detalles Bibliográficos
Autores principales: Ortega‐Paz, Luis, Cristóbal, Helena, Ortiz‐Perez, José Tomás, García de Frutos, Pablo, Mendieta, Guiomar, Sandoval, Elena, Rodriguez, Juan José, Ortega, Emilio, García‐Álvarez, Ana, Brugaletta, Salvatore, Sabaté, Manel, Dantas, Ana Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871706/
https://www.ncbi.nlm.nih.gov/pubmed/36303443
http://dx.doi.org/10.1002/ehf2.14186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871706/
https://www.ncbi.nlm.nih.gov/pubmed/36303443
http://dx.doi.org/10.1002/ehf2.14186

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