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Blockchains as a means to promote privacy protecting, access availing, incentive increasing, ELSI lessening DNA databases

Not all blockchains are created equal, and many cannot accommodate all of the primary characteristics of big data: Variety, Velocity, Volume and Veracity. Currently, public blockchains are slow and clunky, it can be expensive to keep up with the velocity of genomic data production. Further, the tran...

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Autores principales: Zarchi, Gal, Sherman, Maya, Gady, Omer, Herzig, Tomer, Idan, Ziv, Greenbaum, Dov
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871783/
https://www.ncbi.nlm.nih.gov/pubmed/36703942
http://dx.doi.org/10.3389/fdgth.2022.1028249
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author Zarchi, Gal
Sherman, Maya
Gady, Omer
Herzig, Tomer
Idan, Ziv
Greenbaum, Dov
author_facet Zarchi, Gal
Sherman, Maya
Gady, Omer
Herzig, Tomer
Idan, Ziv
Greenbaum, Dov
author_sort Zarchi, Gal
collection PubMed
description Not all blockchains are created equal, and many cannot accommodate all of the primary characteristics of big data: Variety, Velocity, Volume and Veracity. Currently, public blockchains are slow and clunky, it can be expensive to keep up with the velocity of genomic data production. Further, the transparent and universally accessible nature of public blockchain doesn't necessarily accommodate all of the variety of sequence data, including very private information. Bespoke private permissioned blockchains, however, can be created to optimally accommodate all of the big data features of genomic data. Further, private permissioned chains can be implemented to both protect the privacy and security of the genetic information therein, while also providing access to researchers. An NFT marketplace associated with that private chain can provide the discretized sale of anonymous and encrypted data sets while also incentivizing individuals to share their data through payments mediated by smart contracts. Private blockchains can provide a transparent chain of custody for each use of the customers' data, and validation that this data is not corrupted. However, even with all of these benefits there remain some concerns with the implementation of this new technology including the ethical, legal and social implications typically associated with DNA databases.
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spelling pubmed-98717832023-01-25 Blockchains as a means to promote privacy protecting, access availing, incentive increasing, ELSI lessening DNA databases Zarchi, Gal Sherman, Maya Gady, Omer Herzig, Tomer Idan, Ziv Greenbaum, Dov Front Digit Health Digital Health Not all blockchains are created equal, and many cannot accommodate all of the primary characteristics of big data: Variety, Velocity, Volume and Veracity. Currently, public blockchains are slow and clunky, it can be expensive to keep up with the velocity of genomic data production. Further, the transparent and universally accessible nature of public blockchain doesn't necessarily accommodate all of the variety of sequence data, including very private information. Bespoke private permissioned blockchains, however, can be created to optimally accommodate all of the big data features of genomic data. Further, private permissioned chains can be implemented to both protect the privacy and security of the genetic information therein, while also providing access to researchers. An NFT marketplace associated with that private chain can provide the discretized sale of anonymous and encrypted data sets while also incentivizing individuals to share their data through payments mediated by smart contracts. Private blockchains can provide a transparent chain of custody for each use of the customers' data, and validation that this data is not corrupted. However, even with all of these benefits there remain some concerns with the implementation of this new technology including the ethical, legal and social implications typically associated with DNA databases. Frontiers Media S.A. 2023-01-10 /pmc/articles/PMC9871783/ /pubmed/36703942 http://dx.doi.org/10.3389/fdgth.2022.1028249 Text en © 2023 Zarchi, Sherman, Gady, Herzig, Idan and Greenbaum. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Digital Health
Zarchi, Gal
Sherman, Maya
Gady, Omer
Herzig, Tomer
Idan, Ziv
Greenbaum, Dov
Blockchains as a means to promote privacy protecting, access availing, incentive increasing, ELSI lessening DNA databases
title Blockchains as a means to promote privacy protecting, access availing, incentive increasing, ELSI lessening DNA databases
title_full Blockchains as a means to promote privacy protecting, access availing, incentive increasing, ELSI lessening DNA databases
title_fullStr Blockchains as a means to promote privacy protecting, access availing, incentive increasing, ELSI lessening DNA databases
title_full_unstemmed Blockchains as a means to promote privacy protecting, access availing, incentive increasing, ELSI lessening DNA databases
title_short Blockchains as a means to promote privacy protecting, access availing, incentive increasing, ELSI lessening DNA databases
title_sort blockchains as a means to promote privacy protecting, access availing, incentive increasing, elsi lessening dna databases
topic Digital Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871783/
https://www.ncbi.nlm.nih.gov/pubmed/36703942
http://dx.doi.org/10.3389/fdgth.2022.1028249
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