A Phase 1, open-label, crossover study evaluating the effect of a single dose of sodium zirconium cyclosilicate on the pharmacokinetics of tacrolimus and cyclosporin

BACKGROUND: Sodium zirconium cyclosilicate (SZC) is an oral, highly selective potassium binder approved for the treatment of hyperkalaemia in adults. SZC may change the absorption of co-administered drugs that exhibit pH-dependent bioavailability. This study evaluated whether the pharmacokinetic (PK...

Descripción completa

Detalles Bibliográficos
Autores principales: Någård, Mats, Choudhury, Nurul, Al-Shurbaji, Ayman, Lisovskaja, Vera, Mackillop, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871843/
https://www.ncbi.nlm.nih.gov/pubmed/36726439
http://dx.doi.org/10.1093/ckj/sfac205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871843/
https://www.ncbi.nlm.nih.gov/pubmed/36726439
http://dx.doi.org/10.1093/ckj/sfac205

Ejemplares similares