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Characterizing T cell responses to enzymatically modified beta cell neo-epitopes

INTRODUCTION: Previous studies verify the formation of enzymatically post-translationally modified (PTM) self-peptides and their preferred recognition by T cells in subjects with type 1 diabetes (T1D). However, questions remain about the relative prevalence of T cells that recognize PTM self-peptide...

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Detalles Bibliográficos
Autores principales: Nguyen, Hai, Arribas-Layton, David, Chow, I-Ting, Speake, Cate, Kwok, William W., Hessner, Martin J., Greenbaum, Carla J., James, Eddie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871889/
https://www.ncbi.nlm.nih.gov/pubmed/36703975
http://dx.doi.org/10.3389/fimmu.2022.1015855